Title:
KIT FOR RAPIDLY DETECTING HEPATITIS B VIRUS GENE AND DETECTION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/110335
Kind Code:
A1
Abstract:
Disclosed is a kit for rapidly detecting hepatitis B virus gene and a detection method therefor, which relate to the diagnosis of viral hepatitis B, and the fields of infectious diseases, molecular biology and cell biology. According to the kit and the detection method, the RPA is combined with a gene editing system of CRISPR/Cas13a, so that the hepatitis B virus can be conveniently, rapidly and accurately detected, and the kit and the detection method have good sensitivity and specificity.
Inventors:
ZHU HAIHONG (CN)
CHEN CHAO (CN)
REN YANLI (CN)
CAI XIAOPENG (CN)
CHEN ZHI (CN)
CHEN CHAO (CN)
REN YANLI (CN)
CAI XIAOPENG (CN)
CHEN ZHI (CN)
Application Number:
PCT/CN2020/136280
Publication Date:
June 02, 2022
Filing Date:
December 14, 2020
Export Citation:
Assignee:
UNIV ZHEJIANG (CN)
International Classes:
C12N15/11; C12Q1/70; C12Q1/6844
Foreign References:
CN110343785A | 2019-10-18 | |||
CN109055499A | 2018-12-21 | |||
CN1378553A | 2002-11-06 | |||
CN111778288A | 2020-10-16 | |||
CN110066865A | 2019-07-30 | |||
CN107604096A | 2018-01-19 | |||
CN111041084A | 2020-04-21 | |||
US20020177127A1 | 2002-11-28 | |||
KR20120044953A | 2012-05-08 |
Other References:
CHEN, SHAN, XIE XUE-PING, ZOU CHUN-MEI, QI BING-JIE, ZHOU XIE-MIN, GUO-HUA: " Detection methods and devices of visual detection in closed tube recombinase polymerase amplification of hepatitis B virus", JOURNAL OF MEDICAL POSTGRADUATES, vol. 33, no. 5, 1 May 2020 (2020-05-01), pages 515 - 520, XP055933985
Attorney, Agent or Firm:
HANGZHOU ZHONGCHENG PATENT AGENCY CO., LTD. (CN)
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