Title:
L-CARNITINE FOR TREATMENT OF HEARING LOSS
Document Type and Number:
WIPO Patent Application WO2003063789
Kind Code:
A3
Abstract:
Preferred embodiments of the current invention relate to methods of preventing and/or treating hearing loss by administration of L-carnitine or its derivatives. More particularly, administration of L-carnitine or its derivatives is disclosed for preventing and/or treating hearing loss caused to mothers and/or their offspring during the perinatal period by the ototoxic effects of chemotherapeutic agents, aminoglycoside antibiotics, as well as excess noise.
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Inventors:
KALINEC GILDA M (US)
KALINEC FEDERICO (US)
LIM DAVID J (US)
KALINEC FEDERICO (US)
LIM DAVID J (US)
Application Number:
PCT/US2003/002832
Publication Date:
January 22, 2004
Filing Date:
January 30, 2003
Export Citation:
Assignee:
HOUSE EAR INST (US)
KALINEC GILDA M (US)
KALINEC FEDERICO (US)
LIM DAVID J (US)
KALINEC GILDA M (US)
KALINEC FEDERICO (US)
LIM DAVID J (US)
International Classes:
A61K31/205; A61K31/22; A61K31/221; A61K45/06; (IPC1-7): A61K31/205; A61K31/221
Foreign References:
US5977162A | 1999-11-02 |
Other References:
KALINEC ET AL.: "Inner ear cell lines as an in vitro system for drug ototoxicity screening", ARO ABSTRACTS, vol. 25, no. 139, 2002, pages 36, XP002967244
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