Title:
LIGHT-SHEET MICROSCOPE, CONTROL METHOD, AND PROGRAM
Document Type and Number:
WIPO Patent Application WO/2021/166069
Kind Code:
A1
Abstract:
This light-sheet microscope (1) is provided with: a lighting optical system (20); an observation optical system (30); a parallel-planar plate (11); and a control device (80). The lighting optical system (20) comprises an objective lens (21) having a first optical axis, and forms a light sheet on a sample (S). The observation optical system (30) comprises an objective lens (31) having a second optical axis intersecting with the first optical axis, and forms an optical image of the sample (S) on the basis of light coming from the sample (S). The parallel-planar plate (11) regulates the incident position of light entering the objective lens (21) in a direction intersecting with the first optical axis. The control device (80) controls the parallel-planar plate (11) on the basis of the refractive indices of two or more media so as to make an observation plane and the light sheet parallel to each other. The two or more media have mutually different refractive indices, are arranged on a light path extending from the objective lens (21) up to the objective lens (31) by way of the sample (S), and each have, on the optical path, an interface so as not to be orthogonal to the first axis or the second axis.
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Inventors:
SHIMADA YOSHIHIRO (JP)
Application Number:
PCT/JP2020/006248
Publication Date:
August 26, 2021
Filing Date:
February 18, 2020
Export Citation:
Assignee:
OLYMPUS CORP (JP)
International Classes:
G02B21/02; G02B21/06
Foreign References:
| JP2019207403A | 2019-12-05 | |||
| JP2003279860A | 2003-10-02 | |||
| JP2019074594A | 2019-05-16 | |||
| JP2018004777A | 2018-01-11 | |||
| JP2019530006A | 2019-10-17 | |||
| JPH08271230A | 1996-10-18 |
Attorney, Agent or Firm:
OSUGA, Yoshiyuki et al. (JP)
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