Title:
A LIVE BACTERIA STRAIN WITH REDUCED CAPSULES
Document Type and Number:
WIPO Patent Application WO/2024/002331
Kind Code:
A1
Abstract:
A live bacteria strain with reduced capsules is provided. More particularly, a live bacteria strain (for example, a live Staphylococcus aureus strain) in which the production of capsules is reduced, to a vaccine against bacterial infection comprising said live strain, and a method for preventing and/or treating bacterial infection in a subject by administering said live strain.
Inventors:
LIN QIUBIN (CN)
ZHANG MENGYA (CN)
WANG MINGRUI (CN)
LEE MING-CHUN (CN)
ZHANG MENGYA (CN)
WANG MINGRUI (CN)
LEE MING-CHUN (CN)
Application Number:
PCT/CN2023/104567
Publication Date:
January 04, 2024
Filing Date:
June 30, 2023
Export Citation:
Assignee:
SHANGHAI YUGUAN BIOTECH CO LTD (CN)
International Classes:
C12N1/21; A61K35/74; A61P31/04
Domestic Patent References:
| WO2021233420A1 | 2021-11-25 |
Foreign References:
| CN101397547A | 2009-04-01 | |||
| CN102719389A | 2012-10-10 | |||
| US20160074497A1 | 2016-03-17 |
Other References:
HU, D.; WANG, CHANG-JUN; PAN, XIU-ZHEN; TANG, JIA-Q: "Characterization of a nonencapsulated mutant of Streptococcus suis serotype 2 and evaluation of its protective abilities in a mouse model", MICROBIOLOGY CHINA, INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES; CHINESE MICROBIOLOGY, CN, vol. 38, no. 1, 20 January 2011 (2011-01-20), CN , pages 85 - 90, XP009551995, ISSN: 0253-2654, DOI: 10.13344/j.microbiol.china.2011.01.020
CHAO F U, LIU MENG-YUE, ZHAO RUI-LI, CORRESPONDING H U, YE JI-FEI, JUN CUI: "Research Advances of Adhesion Mechanism and Pathogenic Factor in Streptococcus suis", JOURNAL OF TIANJIN AGRICULTURAL UNIVERSITY, vol. 24, no. 4, 31 December 2017 (2017-12-31), pages 77 - 80, XP093122100
CHAO F U, LIU MENG-YUE, ZHAO RUI-LI, CORRESPONDING H U, YE JI-FEI, JUN CUI: "Research Advances of Adhesion Mechanism and Pathogenic Factor in Streptococcus suis", JOURNAL OF TIANJIN AGRICULTURAL UNIVERSITY, vol. 24, no. 4, 31 December 2017 (2017-12-31), pages 77 - 80, XP093122100
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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