Title:
LIVING ORGANISM HAVING L-LACTIC ACID UTILIZING CHARACTERISTICS, AND RESOURCE RECYCLING METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2023/106300
Kind Code:
A1
Abstract:
The present disclosure provides a system for culturing animal cells by using, as a source of nutrient, components derived from a living organism such as algae, and for reutilizing a waste culture liquid obtained therefrom. The present disclosure provides a living organism or a cultured cell, which has undergone a modification. Said modification includes providing or enhancing the ability to utilize L-lactic acid in the living organism or the cultured cell. The present disclosure also provides a method for culturing, in recycling-oriented manner, at least two types of cells, which are cell X and cell Y, the method comprising: a step (a) for providing components excreted from the cell X to the cell Y; a step (b) for providing components originating from the cell Y to the cell X; a step (c) for culturing the cell X and the cell Y; and, as necessary, a step (d) for repeating steps (a)-(c). At least one of the components excreted from the cell X is a component that can be utilized by the cell Y. At least one of the components originating from the cell Y is a nutritional component for the cell X.
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Inventors:
HASUNUMA TOMOHISA (JP)
KATO YUICHI (JP)
INABE KOSUKE (JP)
KONDO AKIHIKO (JP)
SHIMIZU TATSUYA (JP)
HARAGUCHI YUJI (JP)
KATO YUICHI (JP)
INABE KOSUKE (JP)
KONDO AKIHIKO (JP)
SHIMIZU TATSUYA (JP)
HARAGUCHI YUJI (JP)
Application Number:
PCT/JP2022/044962
Publication Date:
June 15, 2023
Filing Date:
December 06, 2022
Export Citation:
Assignee:
UNIV KOBE NAT UNIV CORP (JP)
UNIV TOKYO WOMENS MEDICAL (JP)
UNIV TOKYO WOMENS MEDICAL (JP)
International Classes:
A23L13/00; C12P13/04; C12N1/00; C12N1/12; C12N1/13; C12N1/15; C12N1/19; C12N1/21; C12N5/07; C12N5/077; C12N5/10; C12N15/31; C12N15/52; C12N15/53; C12P7/56; C12P7/62; C12P19/04; C12Q1/04; C12Q1/68
Domestic Patent References:
| WO2010032697A1 | 2010-03-25 | |||
| WO2021066113A1 | 2021-04-08 | |||
| WO2022250165A1 | 2022-12-01 |
Foreign References:
| JP2011200161A | 2011-10-13 | |||
| JPS63173596A | 1988-07-18 |
Other References:
HIROKAWA YASUTAKA; GOTO RYOTA; UMETANI YOSHITAKA; HANAI TAIZO: "Construction of a noveld-lactate producing pathway from dihydroxyacetone phosphate of the Calvin cycle in cyanobacterium,Synechococcus elongatusPCC 7942", JOURNAL OF BIOSCIENCE AND BIOENGINEERING, ELSEVIER, AMSTERDAM, NL, vol. 124, no. 1, 18 March 2017 (2017-03-18), NL , pages 54 - 61, XP085111235, ISSN: 1389-1723, DOI: 10.1016/j.jbiosc.2017.02.016
K. MCNEELY, Y. XU, N. BENNETTE, D. A. BRYANT, G. C. DISMUKES: "Redirecting Reductant Flux into Hydrogen Production via Metabolic Engineering of Fermentative Carbon Metabolism in a Cyanobacterium", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 76, no. 15, 1 August 2010 (2010-08-01), US , pages 5032 - 5038, XP055273014, ISSN: 0099-2240, DOI: 10.1128/AEM.00862-10
TATSUYA SHIMIZU ET AL.: "3G15 Circular Food Production System Using Algae/Animal Cell Recycling Culture", PROCEEDINGS OF THE 64TH SPACE SCIENCE AND TECHNOLOGY CONFERENCE; [ONLINE]; OCTOBER 27-30, 2020, vol. 64, no. JSASS-2020-4478-3G15, 1 January 2020 (2020-01-01) - 30 October 2020 (2020-10-30), pages 1, XP009546740
YAMANAKA KUMIKO, TATSUYA SHIMIZU: "Development of sustainable culture media", SEIBUTSU KOGAKU KAISHI = JOURNAL OF THE SOCIETY FOR BIOSCIENCE AND BIOENGINEERING, JAPAN, NIPPON SEIBUTSU KOGAKKAI, SUITA,, JP, vol. 100, no. 4, 25 April 2022 (2022-04-25), JP , pages 165 - 168, XP093069570, ISSN: 0919-3758, DOI: 10.34565/seibutsukogaku.100.4_165
加藤 悠一 他, 動物細胞培養廃液のリサイクルに向けたL-乳酸資化性ラン藻の開発, 第74回日本生物工学会大会講演要旨集, 17 October 2022, vol. 74th, p. 90, 2B02-08
K. MCNEELY, Y. XU, N. BENNETTE, D. A. BRYANT, G. C. DISMUKES: "Redirecting Reductant Flux into Hydrogen Production via Metabolic Engineering of Fermentative Carbon Metabolism in a Cyanobacterium", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 76, no. 15, 1 August 2010 (2010-08-01), US , pages 5032 - 5038, XP055273014, ISSN: 0099-2240, DOI: 10.1128/AEM.00862-10
TATSUYA SHIMIZU ET AL.: "3G15 Circular Food Production System Using Algae/Animal Cell Recycling Culture", PROCEEDINGS OF THE 64TH SPACE SCIENCE AND TECHNOLOGY CONFERENCE; [ONLINE]; OCTOBER 27-30, 2020, vol. 64, no. JSASS-2020-4478-3G15, 1 January 2020 (2020-01-01) - 30 October 2020 (2020-10-30), pages 1, XP009546740
YAMANAKA KUMIKO, TATSUYA SHIMIZU: "Development of sustainable culture media", SEIBUTSU KOGAKU KAISHI = JOURNAL OF THE SOCIETY FOR BIOSCIENCE AND BIOENGINEERING, JAPAN, NIPPON SEIBUTSU KOGAKKAI, SUITA,, JP, vol. 100, no. 4, 25 April 2022 (2022-04-25), JP , pages 165 - 168, XP093069570, ISSN: 0919-3758, DOI: 10.34565/seibutsukogaku.100.4_165
加藤 悠一 他, 動物細胞培養廃液のリサイクルに向けたL-乳酸資化性ラン藻の開発, 第74回日本生物工学会大会講演要旨集, 17 October 2022, vol. 74th, p. 90, 2B02-08
Attorney, Agent or Firm:
YAMAMOTO, Shusaku et al. (JP)
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