Title:
MACROCYCLIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS COMPRISING N-CYCLIC P2 MOIETIES
Document Type and Number:
WIPO Patent Application WO2001077113
Kind Code:
A3
Abstract:
The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
Inventors:
CHEN KEVIN X
ARASAPPAN ASHOK
VENKATRAMAN SRIKANTH
PAREKH TEJAL N
GU HAINING
NJOROGE F GEORGE
GIRIJAVALLABHAN VIYYOOR M
GANGULY ASHIT
SAKSENA ANIL
JAO EDWIN
YAO NANHUA H
PRONGAY ANDREW J
MADISON VINCENT S
VIBULBHAN BANCHA
ARASAPPAN ASHOK
VENKATRAMAN SRIKANTH
PAREKH TEJAL N
GU HAINING
NJOROGE F GEORGE
GIRIJAVALLABHAN VIYYOOR M
GANGULY ASHIT
SAKSENA ANIL
JAO EDWIN
YAO NANHUA H
PRONGAY ANDREW J
MADISON VINCENT S
VIBULBHAN BANCHA
Application Number:
PCT/US2001/010869
Publication Date:
June 20, 2002
Filing Date:
April 03, 2001
Export Citation:
Assignee:
SCHERING CORP (US)
International Classes:
A61K31/7052; A61K38/08; A61K38/21; A61K38/55; A61K45/00; A61P31/12; A61P31/14; A61P43/00; C07K1/02; C07K5/023; C12N9/99; C07K5/08; C07K5/083; C07K5/12; C07K7/02; A61K38/00; (IPC1-7): C07K7/06; C07K14/18; C07K5/062; C07K5/065; C07K5/087; C07K5/107; A61K38/05; A61K38/06; A61K38/07; A61K38/08; A61P31/14
Domestic Patent References:
| WO2000009558A1 | 2000-02-24 | |||
| WO1999007734A2 | 1999-02-18 |
Other References:
See also references of EP 1268525A2
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