Title:
MEASURING DEVICE AND MEASURING METHOD
Document Type and Number:
WIPO Patent Application WO/2015/115221
Kind Code:
A1
Abstract:
An objective of the present invention is to provide a measuring device for which the need for adjustment of a coherence optical assembly when changing a molecule to be measured is eliminated. A measuring device (1) comprises: a light source unit (10) which emits a pump beam (PP), a Stokes beam (ST), and a signal beam (SG); a light projection unit (20) which projects the pump beam (PP) and the Stokes beam (ST) upon a subject (S); a light modulation unit (30) which modulates the wavelength of the signal beam (SG); a first light detection unit (50) which detects coherent light between the wavelength-modulated signal beam (SG) and an anti-Stokes beam (AS) from the subject (S); a second light detection unit (52) which detects coherent light between the signal beam (SG) and the wavelength-modulated signal beam (SG); and a signal detection unit (60) which detects, from the signal from the first light detection unit (50), a component which is 90° out of phase with the signal from the second light detection unit (52). An optical parametric oscillator (12) of the light source unit (10) further comprises two nonlinear optical crystals which rotate to incline at the same angle in opposite directions with respect to the optical path.
Inventors:
TOIDA MASAHIRO (JP)
Application Number:
PCT/JP2015/051194
Publication Date:
August 06, 2015
Filing Date:
January 19, 2015
Export Citation:
Assignee:
UNIV SAITAMA MEDICAL (JP)
International Classes:
G02F1/39; A61B5/1455; G01N21/65; G02F1/35
Domestic Patent References:
| WO2013129412A1 | 2013-09-06 |
Foreign References:
| JP2008502915A | 2008-01-31 | |||
| JPH04257283A | 1992-09-11 | |||
| JP2010099095A | 2010-05-06 |
Other References:
M. JURNA ET AL.: "Background free CARS imaging by phase sensitive heterodyne CARS", OPTICS EXPRESS, vol. 16, no. 20, 29 September 2008 (2008-09-29), pages 15863 - 15869, XP055215547
MASAHIRO TOIDA: "Coherent Anti-Stokes Raman Scattering ni yoru Mushinshu Kettochi Monitor no Kenkyu", JOURNAL OF SAITAMA MEDICAL UNIVERSITY, vol. 39, no. 1, August 2012 (2012-08-01), pages 19 - 23, XP008174258
MASAHIRO TOIDA: "Coherent Anti-Stokes Raman Scattering ni yoru Mushinshu Kettochi Monitor no Kenkyu", JOURNAL OF SAITAMA MEDICAL UNIVERSITY, vol. 39, no. 1, August 2012 (2012-08-01), pages 19 - 23, XP008174258
Attorney, Agent or Firm:
FUSE, Yukio et al. (JP)
Yukio Fuse (JP)
Yukio Fuse (JP)
Download PDF: