Title:
MEDICAMENT FOR PREVENTING OR TREATING ARRHYTHMIA AFTER CATHETER ABLATION SURGERY
Document Type and Number:
WIPO Patent Application WO/2020/218228
Kind Code:
A1
Abstract:
Provided is a means for preventing or treating arrhythmia such as atrial fibrillation after catheter ablation surgery. One aspect of the present invention relates to a medicament for preventing or treating arrhythmia after catheter ablation surgery, the medicament containing, as an active agent, adrenomedullin or a derivative thereof having adrenomedullin activity. Another aspect of the present invention relates to a pharmaceutical composition for preventing or treating arrhythmia after catheter ablation surgery, the pharmaceutical composition containing adrenomedullin or a derivative thereof having adrenomedullin activity and one or more pharmaceutically acceptable carriers.
Inventors:
KITAMURA KAZUO (JP)
IDEGUCHI TAKESHI (JP)
KITA TOSHIHIRO (JP)
IDEGUCHI TAKESHI (JP)
KITA TOSHIHIRO (JP)
Application Number:
PCT/JP2020/017001
Publication Date:
October 29, 2020
Filing Date:
April 20, 2020
Export Citation:
Assignee:
UNIV MIYAZAKI (JP)
International Classes:
A61P9/06; A61K38/16; C07K14/46; C12N15/12
Foreign References:
| JP4830093B2 | 2011-12-07 |
Other References:
OHSAKA, SHUNJI ET AL.: "Experimental study about the cardiac surgery myocardial disorder reduction with the P-533 adrenomedullin administration", GENERAL THORACIC AND CARDIOVASCULAR SURGERY, vol. 55, 2007, pages 430, P-533
LOOI, YEE HOO ET AL.: "Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetizec rats", BRITISH JOURNAL OF PHARMACOLOGY, vol. 148, 2006, pages 599 - 609, XP055758936
MEDICAL ETHICS COMMITTEE, FACULTY OF MEDICINE, MIYAZAKI UNIVERSITY, REPORT OF THE MEDICAL ETHICS COMMITTEE, FACULTY OF MEDICINE, MIYAZAKI UNIVERSITY (MEETING HELF MARCH 22, 2018). SUMMARY OF PROCEEDINGS, Retrieved from the Internet
LOOI, YEE HOO ET AL.: "Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetizec rats", BRITISH JOURNAL OF PHARMACOLOGY, vol. 148, 2006, pages 599 - 609, XP055758936
MEDICAL ETHICS COMMITTEE, FACULTY OF MEDICINE, MIYAZAKI UNIVERSITY, REPORT OF THE MEDICAL ETHICS COMMITTEE, FACULTY OF MEDICINE, MIYAZAKI UNIVERSITY (MEETING HELF MARCH 22, 2018). SUMMARY OF PROCEEDINGS, Retrieved from the Internet
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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