Title:
METHOD AGAINST SNAKE ENVENOMATION
Document Type and Number:
WIPO Patent Application WO/2024/032710
Kind Code:
A1
Abstract:
A method against snake envenomation includes administering to a subject in need thereof a pharmaceutical composition containing a flavonoid compound. The flavonoid compound is selected from the group consisting of isorhamnetin, quercetin, and a combination thereof.
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Inventors:
WU WEN-GUEY (CN)
HUANG LI-KIN (CN)
LIN I-JIN (CN)
HUANG LI-KIN (CN)
LIN I-JIN (CN)
Application Number:
PCT/CN2023/112205
Publication Date:
February 15, 2024
Filing Date:
August 10, 2023
Export Citation:
Assignee:
UBI PHARMA INC (CN)
WU WEN GUEY (CN)
WU WEN GUEY (CN)
International Classes:
A61K31/352; A61P39/02
Foreign References:
| CN114699401A | 2022-07-05 | |||
| CN102178675A | 2011-09-14 |
Other References:
RAGHAVAN SRIMATHI, JAYARAMAN GURUNATHAN: "Synergistic effect of flavonoids combined with antivenom on neutralisation of Naja naja venom", ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE, ELSEVIER, CHINA, vol. 11, no. 7, 1 January 2021 (2021-01-01), China , pages 298, XP093139097, ISSN: 2221-1691, DOI: 10.4103/2221-1691.309665
AL-ASMARI ABDULRAHMAN K.; KHAN HASEEB A.; MANTHIRI RAJAMOHAMED A.; AL-KHLAIWI AHMAD A.; AL-ASMARI BAYAN A.; IBRAHIM KHALID E.: "Protective effects of a natural herbal compound quercetin against snake venom-induced hepatic and renal toxicities in rats", FOOD AND CHEMICAL TOXICOLOGY, PERGAMON, GB, vol. 118, 8 May 2018 (2018-05-08), GB , pages 105 - 110, XP085440713, ISSN: 0278-6915, DOI: 10.1016/j.fct.2018.05.016
COTRIM, C.A. ; DE OLIVEIRA, S.C.B. ; DIZ FILHO, E.B.S. ; FONSECA, F.V. ; BALDISSERA, L. ; ANTUNES, E. ; XIMENES, R.M. ; MONTEIRO, : "Quercetin as an inhibitor of snake venom secretory phospholipase A2", CHEMICO-BIOLOGICAL INTERACTIONS., ELSEVIER SCIENCE IRLAND., IR, vol. 189, no. 1-2, 15 January 2011 (2011-01-15), IR , pages 9 - 16, XP027583251, ISSN: 0009-2797
DENG QIUPING; HE QIYI; ZHANG YINGZHENG; YU XIAODONG: "Progress on Active Components from Natural Plants against Snake Venoms", JOURNAL OF CHONGQING NORMAL UNIVERSITY (NATURAL SCIENCE), CHONGQING NORMAL UNIVERSITY, CN, vol. 33, no. 6, 2 November 2016 (2016-11-02), CN , pages 131 - 136, XP009552605, ISSN: 1672-6693
BHAVYA JANARDHAN;VINEETHA M SHRIKANTH;KIRAN K MIRAJKAR;SUNIL S MORE: "In vitro screening and evaluation of antivenom phytochemicals from Azima tetracantha Lam. leaves against Bungarus caeruleus and Vipera russelli", JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES, UNIVERSIDADE ESTADUAL PAULISTA JULIO DE MESQUITA FILHO, BR, vol. 20, no. 1, 1 April 2014 (2014-04-01), BR , pages 12, XP021183446, ISSN: 1678-9199, DOI: 10.1186/1678-9199-20-12
AL-ASMARI ABDULRAHMAN K.; KHAN HASEEB A.; MANTHIRI RAJAMOHAMED A.; AL-KHLAIWI AHMAD A.; AL-ASMARI BAYAN A.; IBRAHIM KHALID E.: "Protective effects of a natural herbal compound quercetin against snake venom-induced hepatic and renal toxicities in rats", FOOD AND CHEMICAL TOXICOLOGY, PERGAMON, GB, vol. 118, 8 May 2018 (2018-05-08), GB , pages 105 - 110, XP085440713, ISSN: 0278-6915, DOI: 10.1016/j.fct.2018.05.016
COTRIM, C.A. ; DE OLIVEIRA, S.C.B. ; DIZ FILHO, E.B.S. ; FONSECA, F.V. ; BALDISSERA, L. ; ANTUNES, E. ; XIMENES, R.M. ; MONTEIRO, : "Quercetin as an inhibitor of snake venom secretory phospholipase A2", CHEMICO-BIOLOGICAL INTERACTIONS., ELSEVIER SCIENCE IRLAND., IR, vol. 189, no. 1-2, 15 January 2011 (2011-01-15), IR , pages 9 - 16, XP027583251, ISSN: 0009-2797
DENG QIUPING; HE QIYI; ZHANG YINGZHENG; YU XIAODONG: "Progress on Active Components from Natural Plants against Snake Venoms", JOURNAL OF CHONGQING NORMAL UNIVERSITY (NATURAL SCIENCE), CHONGQING NORMAL UNIVERSITY, CN, vol. 33, no. 6, 2 November 2016 (2016-11-02), CN , pages 131 - 136, XP009552605, ISSN: 1672-6693
BHAVYA JANARDHAN;VINEETHA M SHRIKANTH;KIRAN K MIRAJKAR;SUNIL S MORE: "In vitro screening and evaluation of antivenom phytochemicals from Azima tetracantha Lam. leaves against Bungarus caeruleus and Vipera russelli", JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES, UNIVERSIDADE ESTADUAL PAULISTA JULIO DE MESQUITA FILHO, BR, vol. 20, no. 1, 1 April 2014 (2014-04-01), BR , pages 12, XP021183446, ISSN: 1678-9199, DOI: 10.1186/1678-9199-20-12
Attorney, Agent or Firm:
TIE CHI PATENT FIRM (CN)
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