METHOD AND APPARATUS FOR SEPARATING AND PURIFYING MINUTE USEFUL SUBSTANCE

WIPO Patent Application WO/2022/250036

A1

[Problem] To provide a method for separating and purifying a minute useful substance. [Solution] A method for separating and purifying a minute useful substance involves filtering a liquid containing the minute useful substance by means of a hollow fiber membrane which has an inner diameter of 0.2-1.4 mm and a molecular weight cut-off of 100,000-1,000,000, wherein: the filtering process comprises a first filtering step for pressing and filtering the liquid containing the minute useful substance from a first opening on one end side of the hollow fiber membrane and separating the liquid into a permeate and a first concentrate, and a second filtering step for pressing and filtering the first concentrate from a second opening on the other end side of the hollow fiber membrane, and separating the first concentrate into a permeate and a second concentrate; and a concentrate having an increased concentration of the minute useful substance is obtained by filtration in which the first filtering step and the second filtering step are alternately carried out multiple times at a membrane surface rate of 0.3-2 m/sec.

NAKATSUKA SHUJI (JP)
INADA AKIO (JP)

PCT/JP2022/021194

December 01, 2022

May 24, 2022

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DAICEN MEMBRANE SYSTEMS LTD (JP)

C07K1/34; B01D61/14; B01D61/58; B01D63/02; B01D69/00; B01D69/02; B01D69/08; C12M1/12

JP2018076291A	2018-05-17
JP2020526190A	2020-08-31
US20190276790A1	2019-09-12
JP2015530110A	2015-10-15
JPH0339084B2	1991-06-12
JP2018076291A	2018-05-17

FURUYA Satoshi (JP)

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