Title:
A METHOD AND COMPOSITION FOR TREATMENT OF A CANCER
Document Type and Number:
WIPO Patent Application WO/2021/121277
Kind Code:
A1
Abstract:
A method for treating a cancer is disclosed, comprising administering to a subject in need thereof a Staphylococcal enterotoxin with or without one or more active ingredients selected from the group consisting of oligomeric proanthocyanidins, quercetin, hesperidin, genistein, daidzein and reveratrol. A composition for treating a cancer comprising a Staphylococcal enterotoxin is also disclosed.
Inventors:
TUAN MEI-NAN (CN)
Application Number:
PCT/CN2020/136849
Publication Date:
June 24, 2021
Filing Date:
December 16, 2020
Export Citation:
Assignee:
TUAN MEI NAN (CN)
International Classes:
A61K38/16; A61K31/05; A61K31/122; A61K31/352; A61K31/353; A61K31/375; A61K31/7048; A61P35/00
Domestic Patent References:
| WO2008127298A2 | 2008-10-23 |
Foreign References:
| US6126945A | 2000-10-03 | |||
| US6126945A | 2000-10-03 | |||
| CN101391096A | 2009-03-25 |
Other References:
KENNETH A NEWELL, ELLENHORN JOSHUA D I, BRUCE DAVID S, BLUESTONEMII JEFFREY A: "In vivo T-cell activation by staphylococcal enterotoxin B prevents outgrowth of a malignant tumor", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 88, no. 3, 1 February 1991 (1991-02-01), pages 1074 - 1078, XP055821559, DOI: 10.1073/pnas.88.3.1074
FRANK G.E. PERABO, PATRICIA L. WILLERT, ANDREAS WIRGER, DORIS H. SCHMIDT, EVA WARDELMANN, MARIO SITZIA, ALEXANDER VON RUECKER, STE: "Preclinical evaluation of superantigen (Staphylococcal Enterotoxin B) in the intravesical immunotherapy of superficial bladder cancer，", INTERNATIONAL JOURNAL OF CANCER, vol. 115, no. 4, 18 April 2005 (2005-04-18), pages 591 - 598, XP055821563, ISSN: 0020-7136, DOI: 10.1002/ijc.20941
WENBIN ZHAO , YANGYANG LI , WENHUI LIU , DING DING , YINGCHUN XU , LIQIANG PAN , SHUQING CHEN: "Transcytosis， Antitumor Activity and Toxicity of Staphylococcal Enterotoxin C2 as an Oral Administration Protein Drug，", TOXINS, vol. 8, no. 6, 185, 16 June 2016 (2016-06-16), pages 1 - 12, XP055821571, ISSN: 2072-6651, DOI: 10.3390/toxins8060185
HU LU-WEN: "Research Progress of Cyclodextrin and Its Derivatives in Anti-tumor Natural Active Ingredients", STRAIT PHARMACEUTICAL JOURNAL, vol. 31, no. 11, 15 November 2019 (2019-11-15), pages 13 - 18, XP055821603, ISSN: 1006-3765
ZHAO WEN-ZHI ET AL.，: "The anti-tumor mechanism of vitamin C，", ELECTRON. J. METAB. NUTR. CANCER，, vol. 6, no. 4, 9 December 2019 (2019-12-09), pages 409 - 414
FRANK G.E. PERABO, PATRICIA L. WILLERT, ANDREAS WIRGER, DORIS H. SCHMIDT, EVA WARDELMANN, MARIO SITZIA, ALEXANDER VON RUECKER, STE: "Preclinical evaluation of superantigen (Staphylococcal Enterotoxin B) in the intravesical immunotherapy of superficial bladder cancer，", INTERNATIONAL JOURNAL OF CANCER, vol. 115, no. 4, 18 April 2005 (2005-04-18), pages 591 - 598, XP055821563, ISSN: 0020-7136, DOI: 10.1002/ijc.20941
WENBIN ZHAO , YANGYANG LI , WENHUI LIU , DING DING , YINGCHUN XU , LIQIANG PAN , SHUQING CHEN: "Transcytosis， Antitumor Activity and Toxicity of Staphylococcal Enterotoxin C2 as an Oral Administration Protein Drug，", TOXINS, vol. 8, no. 6, 185, 16 June 2016 (2016-06-16), pages 1 - 12, XP055821571, ISSN: 2072-6651, DOI: 10.3390/toxins8060185
HU LU-WEN: "Research Progress of Cyclodextrin and Its Derivatives in Anti-tumor Natural Active Ingredients", STRAIT PHARMACEUTICAL JOURNAL, vol. 31, no. 11, 15 November 2019 (2019-11-15), pages 13 - 18, XP055821603, ISSN: 1006-3765
ZHAO WEN-ZHI ET AL.，: "The anti-tumor mechanism of vitamin C，", ELECTRON. J. METAB. NUTR. CANCER，, vol. 6, no. 4, 9 December 2019 (2019-12-09), pages 409 - 414
Attorney, Agent or Firm:
GE CHENG & CO., LTD (CN)
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