Title:
METHOD FOR CULTIVATING A CARTILAGE REPLACEMENT AND A BIOMATRIX PRODUCED ACCORDING TO THIS METHOD
Document Type and Number:
WIPO Patent Application WO2001092473
Kind Code:
A3
Abstract:
The invention relates to methods for cultivating cartilage cells, to methods for the redifferentiation of dedifferentiated cartilage cells and to cartilage transplants.
Inventors:
NOLL MICHAELA (DE)
SCHANDAR MARKUS (DE)
GRAEVE THOMAS (DE)
SCHANDAR MARKUS (DE)
GRAEVE THOMAS (DE)
Application Number:
PCT/EP2001/006073
Publication Date:
June 27, 2002
Filing Date:
May 29, 2001
Export Citation:
Assignee:
FRAUNHOFER GES FORSCHUNG (DE)
NOLL MICHAELA (DE)
SCHANDAR MARKUS (DE)
GRAEVE THOMAS (DE)
NOLL MICHAELA (DE)
SCHANDAR MARKUS (DE)
GRAEVE THOMAS (DE)
International Classes:
C12Q1/02; A61F2/28; A61L27/24; A61L27/38; A61L27/60; C12N5/00; C12N5/071; C12N5/077; G01N33/50; G01N33/566; A61K35/12; (IPC1-7): A61L27/24; A61L27/38
Domestic Patent References:
| WO2000078370A1 | 2000-12-28 | |||
| WO1998051317A1 | 1998-11-19 | |||
| WO1995033821A1 | 1995-12-14 |
Foreign References:
| EP1027897A1 | 2000-08-16 | |||
| US5834029A | 1998-11-10 | |||
| EP0896825A1 | 1999-02-17 | |||
| US5786217A | 1998-07-28 |
Other References:
BUIJA J ET AL: "SYNTHESIS OF HUMAN CARTILAGE USING ORGANOTYPIC CELL CULTURE", ORL, BASEL, CH, vol. 55, 1993, pages 347 - 351, XP001016352, ISSN: 0301-1569
SITTINGER M ET AL: "ENGINEERING OF CARTILAGE TISSUUE USING BIORESORBABLE POLYMER CARRIERS IN PERFUSION CULTURE", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 15, no. 6, 1 May 1994 (1994-05-01), pages 451 - 456, XP002024594, ISSN: 0142-9612
FUJISATO TOSHIA ET AL: "Effect of basic fibroblast growth factor on cartilage regeneration in chondrocyte-seeded collagen sponge scaffold.", BIOMATERIALS, vol. 17, no. 2, 1996, pages 155 - 162, XP002184080, ISSN: 0142-9612
SCHUMAN LEIN ET AL: "Chondrocyte behaviour within different types of collagen gel in vitro.", BIOMATERIALS, vol. 16, no. 10, 1995, pages 809 - 814, XP004032926, ISSN: 0142-9612
SITTINGER M ET AL: "ENGINEERING OF CARTILAGE TISSUUE USING BIORESORBABLE POLYMER CARRIERS IN PERFUSION CULTURE", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 15, no. 6, 1 May 1994 (1994-05-01), pages 451 - 456, XP002024594, ISSN: 0142-9612
FUJISATO TOSHIA ET AL: "Effect of basic fibroblast growth factor on cartilage regeneration in chondrocyte-seeded collagen sponge scaffold.", BIOMATERIALS, vol. 17, no. 2, 1996, pages 155 - 162, XP002184080, ISSN: 0142-9612
SCHUMAN LEIN ET AL: "Chondrocyte behaviour within different types of collagen gel in vitro.", BIOMATERIALS, vol. 16, no. 10, 1995, pages 809 - 814, XP004032926, ISSN: 0142-9612
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