Title:
METHOD FOR EVALUATING HAIR REGENERATION ABILITY OF DERMAL SHEATH CUP (DSC) CELLS, COMPOSITION FOR HAIR REGENERATION AND MANUFACTURING METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/210403
Kind Code:
A1
Abstract:
The present invention provides a method for evaluating the hair regeneration ability of dermal sheath cup (DSC) cells using the expression level of a gene related to smooth muscle differentiation as an indicator. The present invention also provides a composition for hair regeneration that contains DSC cells low-expressing a gene related to smooth muscle differentiation, and a method for manufacturing the same.
Inventors:
YOSHIDA YUZO (JP)
HIGUCHI MIKI (JP)
HIGUCHI MIKI (JP)
Application Number:
PCT/JP2023/015130
Publication Date:
November 02, 2023
Filing Date:
April 14, 2023
Export Citation:
Assignee:
SHISEIDO CO LTD (JP)
International Classes:
C12Q1/6883; A61K35/36; A61L27/38; A61P17/14; C12N5/077
Domestic Patent References:
| WO2019176881A1 | 2019-09-19 | |||
| WO2022191149A1 | 2022-09-15 |
Foreign References:
| JP2021083430A | 2021-06-03 | |||
| JP2022182154A | 2022-12-08 |
Other References:
YOSHIDA YUZO, TAKAHASHI MIKI, YAMANISHI HARUYO, NAKAZAWA YOSUKE, KISHIMOTO JIRO, OHYAMA MANABU: "Changes in the Expression of Smooth Muscle Cell–Related Genes in Human Dermal Sheath Cup Cells Associated with the Treatment Outcome of Autologous Cell–Based Therapy for Male and Female Pattern Hair Loss", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23, no. 13, 27 June 2022 (2022-06-27), pages 7125, XP093103193, DOI: 10.3390/ijms23137125
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
Download PDF: