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Title:
METHOD FOR IN-VITRO PRODUCTION OF TISSUE ENGINEERED AUTO- AND ALLOGRAFTS SUITABLE FOR GUARDED CRYOPRESERVATION
Document Type and Number:
WIPO Patent Application WO/2011/098367
Kind Code:
A3
Abstract:
The invention pertains to a method for the generation of a living cell based tissue engineered organ and/or tissue analogous structure having mechanical and/or functional properties comprising the steps of providing a organ and/or tissue, wherein the organ and/or tissue has the capacity of functioning or forming the native organ/tissue corresponding to the replacement; and wherein the tissue engineered organ and/or tissue analogous structure is made of/contains material incorporating cryoactive substances and/or particles. Furthermore the invention pertains to a scaffold for use in such a method, to a tissue engineered replacement structure made using this method, in particular in the form of a vessel and/or a heart valve.

Inventors:
HOERSTRUP SIMON P (CH)
ZEISBERGER STEFFEN M (CH)
Application Number:
PCT/EP2011/051336
Publication Date:
December 01, 2011
Filing Date:
January 31, 2011
Export Citation:
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Assignee:
UNIV ZUERICH (CH)
HOERSTRUP SIMON P (CH)
ZEISBERGER STEFFEN M (CH)
International Classes:
A61L27/14; A01N1/02; A61L27/36; A61L27/54; A61L27/56; A61L27/58
Domestic Patent References:
WO2009070842A12009-06-11
Attorney, Agent or Firm:
Schmauder & Partner AG (Zürich, CH)
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