METHOD FOR INCREASING YIELD OF METABOLIC PRODUCTS OF SACCHAROMYCES CEREVISIAE

Title:

METHOD FOR INCREASING YIELD OF METABOLIC PRODUCTS OF SACCHAROMYCES CEREVISIAE

Document Type and Number:

WIPO Patent Application WO/2021/114029

Kind Code:

A1

Abstract:

Provided is a GAL gene regulation and control system. In the GAL gene regulation and control system, pCTR3 or pCTR1 is operably linked to the GAL80 gene; and pCUP1 is operably linked to the GAL4 gene. Also provided are a Saccharomyces cerevisiae comprising the GAL gene regulation and control system and a method for increasing the yield of metabolic products of the Saccharomyces cerevisiae.

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Inventors:

XIE WENPING (CN)
CAI YANFENG (CN)
YAO HONGTAO (CN)
WU GUANGJIN (CN)
MAO XINGYAN (CN)
BAO SUMIN (CN)
WAN DAN (CN)

Application Number:

PCT/CN2019/124044

Publication Date:

June 17, 2021

Filing Date:

December 09, 2019

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Assignee:

HEC PHARM CO LTD (CN)

International Classes:

C12N15/113; C12N1/19; C12N15/31; C12P1/02; C12R1/865

Foreign References:

CN105087408A	2015-11-25
CN110373338A	2019-10-25
CN104962488A	2015-10-07
CN105087406A	2015-11-25
US20170088866A1	2017-03-30

Other References:

ZHAMG WU-BING , SHI FENG: "Influences of Gene CRTL on β-carotene Production in Recombinant Saccharomyces Cerevisiae", INDUSTRIAL MICROBIOLOGY, vol. 44, no. 4, 22 August 2014 (2014-08-22), pages 19 - 23, XP009528478, ISSN: 1001-6678
CORINA BORGHOUTS , CHRISTIAN Q SCHECKHUBER , OLIVER STEPHAN , HEINZ D OSIEWACZ: "Copper homeostasis and aging in the fungal model system Podospora anserina: differential expression of PaCtr3 encoding a copper transporter", THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, vol. 34, no. 11, 1 December 2002 (2002-12-01), pages 1355 - 1371, XP055821097, ISSN: 1357-2725, DOI: 10.1016/S1357-2725(02)00078-X

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