Title:
METHOD FOR INTRODUCING POLYNUCLEOTIDE INTO FOLLICULAR CELL, AND COMPOSITION FOR SAID METHOD
Document Type and Number:
WIPO Patent Application WO/2020/262635
Kind Code:
A1
Abstract:
Provided are: a method for introducing a polynucleotide into an ovarian follicle cell, said method including administering an adeno-associated virus vector including the polynucleotide to a subject; and a composition, etc., including an adeno-associated virus vector including the polynucleotide, for introducing the polynucleotide into an ovarian follicle cell.
Inventors:
SHINOHARA TAKASHI (JP)
WATANABE SATOSHI (JP)
SHINOHARA MITO (JP)
WATANABE SATOSHI (JP)
SHINOHARA MITO (JP)
Application Number:
PCT/JP2020/025302
Publication Date:
December 30, 2020
Filing Date:
June 26, 2020
Export Citation:
Assignee:
UNIV KYOTO (JP)
International Classes:
A61K48/00; A01K67/027; A61K31/7088; A61K35/76; A61P15/08; C12N15/864
Other References:
FUJITA, KAZUYUKI ET AL.: "Basic study of gene therapy by FSH receptor gene transfer for in vitro maturation of immature eggs", NIIGATA MEDICAL JOURNAL, vol. 115, no. 10, October 2001 (2001-10-01), pages 548, ISSN: 0029-0440
SHIMADA, TAKASHI: "Development of adeno- associated viral vector", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol. 265, no. 5, 5 May 2018 (2018-05-05), pages 344 - 350, ISSN: 0039- 2359
OZAWA, KEIYA: "Gene therapy using AAV", VIRUS, vol. 57, no. 1, 2007, pages 47 - 55, ISSN: 0042-6857
ZINCARELLI, C. ET AL.: "Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection", MOLECULAR THERAPY, vol. 16, no. 6, 2008, pages 1073 - 1080, XP055338752, ISSN: 1525-0016, DOI: 10.1038/mt.2008.76
GHADAMI M., EL-DEMERDASH E., SALAMA S.A., BINHAZIM A.A., ARCHIBONG A.E., CHEN X., BALLARD B.R., SAIRAM M.R., AL-HENDY A.: "Toward gene therapy of premature ovarian failure: intraovarian injection of adenovirus expressing human FSH receptor restores folliculogenesis in FSHR(-/-) FORKO mice", MOLECULAR HUMAN REPRODUCTION, vol. 16, no. 4, 2010, pages 241 - 250, XP055778963, ISSN: 1360-9947, DOI: 10.1093/molehr/gaq003
TSUZUKI, TOMOKO ET AL.: "Gonadotropin preparations", THE JOURNAL OF PRACTICAL PHARMACY, vol. 68, no. 2, February 2017 (2017-02-01), pages 252 - 257, ISSN: 0044-0035
KUDO, MASATAKA: "Types and characteristics of gonadotropin preparations", OBSTETRICS AND GYNECOLOGY, vol. 86, April 2019 (2019-04-01), pages 13 - 18, ISSN: 0386-9792
SHIMADA, TAKASHI: "Development of adeno- associated viral vector", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol. 265, no. 5, 5 May 2018 (2018-05-05), pages 344 - 350, ISSN: 0039- 2359
OZAWA, KEIYA: "Gene therapy using AAV", VIRUS, vol. 57, no. 1, 2007, pages 47 - 55, ISSN: 0042-6857
ZINCARELLI, C. ET AL.: "Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection", MOLECULAR THERAPY, vol. 16, no. 6, 2008, pages 1073 - 1080, XP055338752, ISSN: 1525-0016, DOI: 10.1038/mt.2008.76
GHADAMI M., EL-DEMERDASH E., SALAMA S.A., BINHAZIM A.A., ARCHIBONG A.E., CHEN X., BALLARD B.R., SAIRAM M.R., AL-HENDY A.: "Toward gene therapy of premature ovarian failure: intraovarian injection of adenovirus expressing human FSH receptor restores folliculogenesis in FSHR(-/-) FORKO mice", MOLECULAR HUMAN REPRODUCTION, vol. 16, no. 4, 2010, pages 241 - 250, XP055778963, ISSN: 1360-9947, DOI: 10.1093/molehr/gaq003
TSUZUKI, TOMOKO ET AL.: "Gonadotropin preparations", THE JOURNAL OF PRACTICAL PHARMACY, vol. 68, no. 2, February 2017 (2017-02-01), pages 252 - 257, ISSN: 0044-0035
KUDO, MASATAKA: "Types and characteristics of gonadotropin preparations", OBSTETRICS AND GYNECOLOGY, vol. 86, April 2019 (2019-04-01), pages 13 - 18, ISSN: 0386-9792
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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