Title:
METHOD FOR ISOLATING EXTRACELLULAR VESICLES USING CATIONS
Document Type and Number:
WIPO Patent Application WO/2019/022542
Kind Code:
A3
Abstract:
The present invention relates to a method for isolating extracellular vesicles using cations, and more particularly, to a method for isolating extracellular vesicles from various samples by using the affinity between the extracellular vesicles and cations. A method for isolating extracellular vesicles according to the present invention does not require expensive equipment, can be applied irrespective of sample amount, and has the advantage of being capable of efficiently isolating the extracellular vesicles while preserving the shape or characteristics thereof. Moreover, the method according to the present invention can be combined with existing isolation methods to maximize extracellular vesicle isolation efficiency, and can be applied to disease diagnosis, disease treatment, and multi-omics research using isolated extracellular vesicles, as well as to research on the properties of extracellular vesicles.
Inventors:
GHO YONG SONG (KR)
LEE CHANG JIN (KR)
KIM JI HYUN (KR)
SONG SUNG HYUN (KR)
LEE CHANG JIN (KR)
KIM JI HYUN (KR)
SONG SUNG HYUN (KR)
Application Number:
PCT/KR2018/008485
Publication Date:
March 28, 2019
Filing Date:
July 26, 2018
Export Citation:
Assignee:
ROSETTA EXOSOME (KR)
POSTECH ACAD IND FOUND (KR)
POSTECH ACAD IND FOUND (KR)
International Classes:
C12N5/00; B01D15/36
Domestic Patent References:
| WO2015048566A1 | 2015-04-02 | |||
| WO2016033695A1 | 2016-03-10 |
Foreign References:
| KR20120023684A | 2012-03-13 | |||
| KR20160116802A | 2016-10-10 |
Other References:
NAKAI ET AL.: "A novel affinity-based method for the isolation of highly purified extracellular vesicles", SCIENTIFIC REPORTS, vol. 6, 2016, pages 1 - 11, XP055566011
See also references of EP 3660142A4
See also references of EP 3660142A4
Attorney, Agent or Firm:
ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)
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