Title:
METHOD FOR PREPARING HIGH-PURITY NAD
Document Type and Number:
WIPO Patent Application WO/2020/056713
Kind Code:
A1
Abstract:
A method for preparing high-purity NAD, comprising: adjusting a pH value to 6.0-8.0, removing insoluble substances, heating to 35 ± 1°C, adding ethanol, cooling to 6 ± 0.5°C, crystallizing, filtering, heating a filtrate to 25-30°C, adjusting the pH value to 1.5-3.0, adding an NAD seed crystal, cooling to 12 ± 0.5°C, crystallizing, adding ethanol again after crystallinity reaching 40%, cooling to 3 ± 0.5°C, crystallizing, filtering after the crystallinity being above 90%, and drying a filter cake to obtain a high-purity NAD product.
Inventors:
ZHANG DONGMIN (CN)
ZHANG QI (CN)
DAI ZHU (CN)
ZHANG QI (CN)
DAI ZHU (CN)
Application Number:
PCT/CN2018/106903
Publication Date:
March 26, 2020
Filing Date:
September 21, 2018
Export Citation:
Assignee:
BONTAC BIO ENG SHENZHEN CO LTD (CN)
BONTAC INVITROLIFE BIO TECH SHENZHEN CO LTD (CN)
JIANGXI BONZYMES BIOTECHNOLOGY CO LTD (CN)
BONTAC INVITROLIFE BIO TECH SHENZHEN CO LTD (CN)
JIANGXI BONZYMES BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07H1/06; C07H19/207
Foreign References:
| CN104876994A | 2015-09-02 | |||
| CN103027947A | 2013-04-10 |
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