Title:
METHOD FOR PRODUCING AMIDE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2018/199147
Kind Code:
A1
Abstract:
Provided is a novel method for producing amide compounds at high stereochemical selectivities. The method according to the present invention for producing amide compounds is provided with an amidation step for reacting, in the presence of a catalyst comprising a metal compound, an amino compound with an aminoester compound represented by general formula (1) to amidate the ester group in the aminoester compound.
Inventors:
YAMAMOTO HISASHI (JP)
MURAMATSU WATARU (JP)
HATTORI TOMOHIRO (JP)
SHIMODA YASUSHI (JP)
MURAMATSU WATARU (JP)
HATTORI TOMOHIRO (JP)
SHIMODA YASUSHI (JP)
Application Number:
PCT/JP2018/016767
Publication Date:
November 01, 2018
Filing Date:
April 25, 2018
Export Citation:
Assignee:
CHUBU UNIV EDUCATIONAL FOUNDATION (JP)
NIPPON PHARMACEUTICAL CHEMICALS CO LTD (JP)
NIPPON PHARMACEUTICAL CHEMICALS CO LTD (JP)
International Classes:
C07C231/02; C07C237/12; C07C269/06; C07C271/22; C07B61/00
Domestic Patent References:
| WO2009060843A1 | 2009-05-14 |
Other References:
TSUJI, HIROAKI ET AL.: "Hydoxy-Directed Amidation of Carboxy lie Acid Esters Using a Tantalum Alkoxide Catalyst", J. AM. CHEM. SOC., vol. 138, no. 43, 2016, pages 14218 - 14221, XP055527397
RENATA, MARCIA DE FIGUEIREDO ET AL.: "Nonclassical Routes for Amide Bond Formation", CHEMICAL REVIEWS, vol. 116, no. 19, 2016, pages 12029 - 12122, XP055527818
ANNU. REV. BIOPHYS. BIOMOL. STRUCT., vol. 34, 2005, pages 91 - 118
TETRAHEDRON, vol. 6, 2005, pages 10827 - 10852
CHEM. REV., vol. 107, 2007, pages 5759 - 5812
CHEM. REV., vol. 111, 2011, pages 6557 - 6602
ORG. PROCESS RES. DEV., vol. 20, no. 2, 2016, pages 140 - 177
CHEM. REV., vol. 116, 2016, pages 12029 - 12122
See also references of EP 3617185A4
RENATA, MARCIA DE FIGUEIREDO ET AL.: "Nonclassical Routes for Amide Bond Formation", CHEMICAL REVIEWS, vol. 116, no. 19, 2016, pages 12029 - 12122, XP055527818
ANNU. REV. BIOPHYS. BIOMOL. STRUCT., vol. 34, 2005, pages 91 - 118
TETRAHEDRON, vol. 6, 2005, pages 10827 - 10852
CHEM. REV., vol. 107, 2007, pages 5759 - 5812
CHEM. REV., vol. 111, 2011, pages 6557 - 6602
ORG. PROCESS RES. DEV., vol. 20, no. 2, 2016, pages 140 - 177
CHEM. REV., vol. 116, 2016, pages 12029 - 12122
See also references of EP 3617185A4
Attorney, Agent or Firm:
TANAKA, Junya et al. (JP)
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