Title:
METHOD FOR PRODUCING CYSTEINE KNOT PROTEIN
Document Type and Number:
WIPO Patent Application WO/2022/191252
Kind Code:
A1
Abstract:
A method for producing a cysteine knot protein, wherein the method for producing a cysteine knot protein comprises a step for culturing transformed mammalian cells containing a gene that encodes the cysteine knot protein and a gene that encodes an exogenous chaperone protein in medium for protein production and producing the cysteine knot protein and a step for recovering the cysteine knot protein produced, in which the chaperone protein includes one or more selected from the group consisting of HSP90α, HSP90β, CDC37, HSP70, HSP40, HSP60, HSP10, HSP110, and HSP27.
Inventors:
NAGATA HIDETAKA (JP)
LIN WENLIEN (JP)
ASADA REIKO (JP)
TAKIKAWA KENJI (JP)
LIN WENLIEN (JP)
ASADA REIKO (JP)
TAKIKAWA KENJI (JP)
Application Number:
PCT/JP2022/010391
Publication Date:
September 15, 2022
Filing Date:
March 09, 2022
Export Citation:
Assignee:
SUMITOMO PHARMA CO LTD (JP)
International Classes:
C12P21/02; C12N5/16; C12N15/12; C12N15/85
Domestic Patent References:
| WO1994008012A1 | 1994-04-14 | |||
| WO2010010848A1 | 2010-01-28 |
Foreign References:
| JP2007524381A | 2007-08-30 | |||
| JP2009273427A | 2009-11-26 | |||
| JP2001517075A | 2001-10-02 | |||
| JP2018532791A | 2018-11-08 | |||
| CN107164333A | 2017-09-15 | |||
| JP2003501014A | 2003-01-14 | |||
| JP2007515962A | 2007-06-21 | |||
| JP2012019699A | 2012-02-02 |
Attorney, Agent or Firm:
FUKAMI PATENT OFFICE, P.C. (JP)
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