Title:
METHOD FOR PRODUCING EXOSOME
Document Type and Number:
WIPO Patent Application WO/2021/029408
Kind Code:
A1
Abstract:
The present invention provides a method for producing an exosome, comprising a step of applying a cell to a cell culture module to culture the cell and a step of producing an exosome by the cell, wherein the cell culture module is provided with a polymer porous film and a casing having at least two culture medium in-flow/out-flow ports and having the polymer porous film placed therein.
Inventors:
HAGIHARA MASAHIKO (JP)
HARADA TAKASHI (JP)
YAMADA SHOTARO (JP)
TAKAMA AKIRA (JP)
HARADA TAKASHI (JP)
YAMADA SHOTARO (JP)
TAKAMA AKIRA (JP)
Application Number:
PCT/JP2020/030613
Publication Date:
February 18, 2021
Filing Date:
August 11, 2020
Export Citation:
Assignee:
UBE INDUSTRIES (JP)
International Classes:
C12M3/00; C12M1/00; C12N5/07; C12N5/071; C12N5/0735; C12N5/074; C12N5/075; C12N5/076; C12N5/0775; C12N5/09; C12N5/10
Domestic Patent References:
| WO2018021368A1 | 2018-02-01 | |||
| WO2018021367A1 | 2018-02-01 | |||
| WO2003054174A1 | 2003-07-03 | |||
| WO2018021368A1 | 2018-02-01 | |||
| WO2009123349A1 | 2009-10-08 | |||
| WO2010038873A1 | 2010-04-08 |
Foreign References:
| JP2019126341A | 2019-08-01 | |||
| JP2018076291A | 2018-05-17 | |||
| JP2019038840A | 2019-03-14 | |||
| JP2009171876A | 2009-08-06 | |||
| JP2018064550A | 2018-04-26 | |||
| JP2011219585A | 2011-11-04 | |||
| JP2011219586A | 2011-11-04 | |||
| JP2009057041W | 2009-03-31 |
Other References:
HARASZTI, R. A. ET AL.: "Exosomes Produced from 3D Cultures of MSCs by Tangential Flow Filtration Show Higher Yield and Improved Activity", MOLECULAR THERAPY, vol. 26, no. 12, 2018, pages 2838 - 2847, XP055751842, DOI: 10.1016/j.ymthe.2018.09.015
AL AMANO, YOSHIHIRO SASAKI, KAZUNARI AKIYOSHI: "#3U07 Development and its bio-function of extracellular vesicles prepared by external field induction", PREPRINTS OF THE 67TH CONFERENCE OF THE SOCIETY OF POLYMER SCIENCE; POLYMER PREPRINTS, JAPAN, SOCIETY OF POLYMER SCIENCE, JAPAN, JP, vol. 67, no. 2, 30 November 2017 (2017-11-30), JP, pages 1 - 3, XP009534253
J. OF EXTRACELLULAR VESICLES, vol. 4, 2015
JAMA ONCOLOGY, vol. 2, 2016, pages 882 - 889
TRENDS IN BIOTECHNOLOGY, vol. 7, 2017, pages 665 - 676
TRANSPLANTATION, vol. 76, 2003, pages 1503 - 10
AM. J. TRANSPLANT., vol. 6, 2006, pages 1541 - 50
INT J ONCOL., vol. 48, no. 5, May 2016 (2016-05-01), pages 1837 - 46
ONCOTARGET, vol. 5, 2014, pages 7748 - 7759
MOLECULAR THERAPY, vol. 26, no. 12, 2018, pages 2838 - 2847
See also references of EP 4012014A4
AL AMANO, YOSHIHIRO SASAKI, KAZUNARI AKIYOSHI: "#3U07 Development and its bio-function of extracellular vesicles prepared by external field induction", PREPRINTS OF THE 67TH CONFERENCE OF THE SOCIETY OF POLYMER SCIENCE; POLYMER PREPRINTS, JAPAN, SOCIETY OF POLYMER SCIENCE, JAPAN, JP, vol. 67, no. 2, 30 November 2017 (2017-11-30), JP, pages 1 - 3, XP009534253
J. OF EXTRACELLULAR VESICLES, vol. 4, 2015
JAMA ONCOLOGY, vol. 2, 2016, pages 882 - 889
TRENDS IN BIOTECHNOLOGY, vol. 7, 2017, pages 665 - 676
TRANSPLANTATION, vol. 76, 2003, pages 1503 - 10
AM. J. TRANSPLANT., vol. 6, 2006, pages 1541 - 50
INT J ONCOL., vol. 48, no. 5, May 2016 (2016-05-01), pages 1837 - 46
ONCOTARGET, vol. 5, 2014, pages 7748 - 7759
MOLECULAR THERAPY, vol. 26, no. 12, 2018, pages 2838 - 2847
See also references of EP 4012014A4
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
Download PDF:
Previous Patent: DYNAMO-ELECTRIC MACHINE CONTROL DEVICE
Next Patent: CELL CULTURING METHOD USING SMALL-PIECE POROUS MEMBRANE
Next Patent: CELL CULTURING METHOD USING SMALL-PIECE POROUS MEMBRANE