Title:
METHOD FOR PRODUCING LIPID HAVING HIGH EICOSAPENTAENOIC ACID CONTENT
Document Type and Number:
WIPO Patent Application WO/2015/005466
Kind Code:
A1
Abstract:
A lipid-producing microorganism capable of efficiently producing EPA is provided. A mutant microorganism obtained by introducing a foreign ∆15 desaturase gene, or a foreign ∆12 desaturase gene and one or both of a foreign ∆15 desaturase gene and a foreign ∆17 desaturase gene, into a microorganism having an ω6 polyunsaturated fatty acid metabolic pathway, the eicosapentaenoic acid content in a fatty acid composition being at least 20% after culturing of the mutant microorganism for 10 days at 20°C or higher.
Inventors:
OGAWA JUN (JP)
ANDO AKINORI (JP)
SAKURADANI EIJI (JP)
SHIMIZU SAKAYU (JP)
HIRAMOTO SHIGERU (JP)
ANDO AKINORI (JP)
SAKURADANI EIJI (JP)
SHIMIZU SAKAYU (JP)
HIRAMOTO SHIGERU (JP)
Application Number:
PCT/JP2014/068539
Publication Date:
January 15, 2015
Filing Date:
July 11, 2014
Export Citation:
Assignee:
UNIV KYOTO (JP)
NISSHIN PHARMA INC (JP)
NISSHIN PHARMA INC (JP)
International Classes:
C12N1/15; A23K1/16; A23L1/30; A61K31/202; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P7/64; A61K8/36; A61P3/06; A61P7/00; A61P7/02; A61P9/10; A61P9/12; A61P29/00; A61P35/00
Foreign References:
| US20100199365A1 | 2010-08-05 | |||
| JP2007515951A | 2007-06-21 | |||
| US20100068761A1 | 2010-03-18 | |||
| JP2010508019A | 2010-03-18 | |||
| JP2012500640A | 2012-01-12 |
Other References:
FEBS LETTERS, vol. 581, 2007, pages 315 - 319
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
Patent business corporation Alga patent firm (JP)
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