Title:
METHOD FOR PRODUCING TYROSINE FROM FERMENTED BROTH
Document Type and Number:
WIPO Patent Application WO/2023/106620
Kind Code:
A1
Abstract:
The present invention relates to a method for producing tyrosine with high purity from a fermented broth containing tyrosine produced by microbial fermentation, the method comprising the steps of: adding a basic solution and dissolving tyrosine therein to obtain a tyrosine dissolved solution; carrying out simultaneous neutralization crystallization to obtain primary tyrosine crystals; adding a base to the primary tyrosine crystals and dissolving same to obtain a tyrosine redissolved solution; and carrying out simultaneous neutralization crystallization by adding an acid to the tyrosine redissolved solution, to obtain secondary tyrosine crystals.
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Inventors:
KANG SEUNG HOON (KR)
PARK YOUNG SOO (KR)
LEE CHUNG YUP (KR)
PARK YOUNG SOO (KR)
LEE CHUNG YUP (KR)
Application Number:
PCT/KR2022/016122
Publication Date:
June 15, 2023
Filing Date:
October 21, 2022
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C07C227/42; C07C229/34; C12P13/22
Foreign References:
| CN111039808A | 2020-04-21 | |||
| CN111957080A | 2020-11-20 | |||
| US3787287A | 1974-01-22 | |||
| JPH031957B2 | 1991-01-11 |
Other References:
PATNAIK, R. ET AL.: "L-tyrosine production by recombinant Escherichia coli: fermentation optimization and recovery", BIOTECHNOLOGY AND BIOENGINEERING, vol. 99, no. 4, 2008, pages 741 - 752, XP071166375, DOI: 10.1002/bit.21765
Attorney, Agent or Firm:
HANOL INTELLECTUAL PROPERTY AND LAW (KR)
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