Title:
METHOD FOR PURIFYING OLIGOSACCHARIDE PEPTIDE USING ULTRAFILTRATION MEMBRANE
Document Type and Number:
WIPO Patent Application WO/2017/110984
Kind Code:
A1
Abstract:
The purpose of the present invention is to purify an SGP substance with high efficiency and in a simple manner. The present invention provides: a method for purifying an SGP substance by means of cross-flow ultrafiltration, said method being characterized by comprising a step of subjecting an aqueous solution containing the SGP substance to a cross-flow ultrafiltration treatment using a primary membrane through which the SGP substance can pass and protein-type impurities cannot pass to produce a filtrate (step A) and a step B of subjecting the filtrate produced in step A to a cross-flow ultrafiltration treatment using a secondary membrane through which the SGP substance cannot pass and low-molecular-weight impurities can pass to produce a concentrated solution (step B); and others.
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Inventors:
OHNUKI TAKASHI (JP)
MIYAUCHI TAKAHIRO (JP)
MIYAUCHI TAKAHIRO (JP)
Application Number:
PCT/JP2016/088309
Publication Date:
June 29, 2017
Filing Date:
December 22, 2016
Export Citation:
Assignee:
DAIICHI SANKYO CO LTD (JP)
International Classes:
C07K1/34; B01D15/32; B01D15/34; B01D15/36; B01D61/14; B01D61/58; B01D71/10; B01D71/68; B01J20/281; B01J47/014
Foreign References:
| JPH06245784A | 1994-09-06 | |||
| JPH0899988A | 1996-04-16 | |||
| JP2007137875A | 2007-06-07 | |||
| JP2003012693A | 2003-01-15 | |||
| JP2011231293A | 2011-11-17 | |||
| JP2011162762A | 2011-08-25 | |||
| JP2011231084A | 2011-11-17 |
Other References:
KOKETSU M. ET AL.: "An efficient preparation and structural characterization of sialylglycopeptides from protease treated egg yolk", JOURNAL OF CARBOHYDRATE CHEMISTRY, vol. 14, no. 6, 1995, pages 833 - 841, XP008182588, DOI: doi:10.1080/07328309508005379
"Maku ni yoru Bunri-ho", 10 October 1982, KODANSHA LTD ., pages: 187 - 188
"Maku ni yoru Bunri-ho", 10 October 1982, KODANSHA LTD ., pages: 187 - 188
Attorney, Agent or Firm:
ISHIBASHI, Koki et al. (JP)
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