Title:
METHOD FOR SCREENING REGULATORY ELEMENT FOR ENHANCING RNA STABILITY OR MRNA TRANSLATION, NEW REGULATORY ELEMENT BASED ON METHOD, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/005577
Kind Code:
A1
Abstract:
The present application relates to a method for screening a regulatory element for enhancing RNA stability and/or mRNA translation, and a novel regulatory element screened by the method. A novel regulatory element for enhancing RNA stability and/or mRNA translation can be obtained through the screening method according to the present application. In addition, such a novel regulatory element may increase the expression of a protein of interest, and thus can be applied to various fields according to the use of the protein of interest.
Inventors:
KIM VIC NARRY (KR)
SEO JENNY (KR)
JUNG SOO-JIN (KR)
SEO JENNY (KR)
JUNG SOO-JIN (KR)
Application Number:
PCT/KR2023/009156
Publication Date:
January 04, 2024
Filing Date:
June 29, 2023
Export Citation:
Assignee:
SEOUL NAT UNIV R&DB FOUNDATION (KR)
INST BASIC SCIENCE (KR)
INST BASIC SCIENCE (KR)
International Classes:
C12Q1/70; C12N15/10; C12Q1/6806
Foreign References:
| JP2022525477A | 2022-05-16 | |||
| KR20220004980A | 2022-01-12 | |||
| JP2007181454A | 2007-07-19 | |||
| KR20090053743A | 2009-05-27 |
Other References:
REN XINGJIE, WANG MENGCHI, LI BINGKUN, JAMIESON KIRSTY, ZHENG LINA, JONES IAN R., LI BIN, TAKAGI MAYA ASAMI, LEE JERRY, MALISKOVA : "Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath", SCIENCE ADVANCES, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, vol. 7, no. 38, 17 September 2021 (2021-09-17), US , XP093121947, ISSN: 2375-2548, DOI: 10.1126/sciadv.abi4360
Attorney, Agent or Firm:
THEWAVE IP LAW FIRM (KR)
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