Title:
METHOD FOR SCREENING FOR THERAPEUTIC AGENT FOR CARTILAGE DISEASES, AND GENETICALLY MODIFIED CARTILAGE CELL FOR USE IN TREATMENT OF CARTILAGE DISEASES
Document Type and Number:
WIPO Patent Application WO/2012/165407
Kind Code:
A1
Abstract:
A substance capable of increasing a cartilage mass and/or capable of normalizing the differentiation into cartilage cells can be screened using salt-inducible kinase 3. A genetically modified cartilage cell in which the expression or function of salt-inducible kinase 3 gene is suppressed or enhanced can be used for ameliorating diseases in which the cartilage mass decreases and/or diseases in which the growth of cartilage is impaired.
Inventors:
TSUMAKI NORIYUKI (JP)
TAKEMORI HIROSHI (JP)
TAKEMORI HIROSHI (JP)
Application Number:
PCT/JP2012/063709
Publication Date:
December 06, 2012
Filing Date:
May 29, 2012
Export Citation:
Assignee:
UNIV KYOTO (JP)
TSUMAKI NORIYUKI (JP)
TAKEMORI HIROSHI (JP)
TSUMAKI NORIYUKI (JP)
TAKEMORI HIROSHI (JP)
International Classes:
C12N15/09; A61K35/00; A61K35/32; A61P19/08; A61P43/00; C12N5/10; C12Q1/48; C12Q1/6897; G01N33/15; A61P19/10
Domestic Patent References:
| WO2010046443A2 | 2010-04-29 |
Foreign References:
| JP2002051786A | 2002-02-19 |
Attorney, Agent or Firm:
IWATANI, Ryo (JP)
Tatsu Iwatani (JP)
Tatsu Iwatani (JP)
Download PDF:
Claims:
Previous Patent: PSYCHIC ENERGIZER AGENT AND PSYCHIC ENERGIZER COMPOSITION
Next Patent: SEATBELT RETRACTOR
Next Patent: SEATBELT RETRACTOR