Title:
METHOD FOR SORTING CELLS
Document Type and Number:
WIPO Patent Application WO/2021/045095
Kind Code:
A1
Abstract:
The present invention pertains to a method for sorting nerve cells on the basis of extracellular potential. More particularly, the method of the present invention comprises: classifying nerve cells by the hierarchical clustering method or principal component analysis (PCA) with the use of extracellular potential parameters before adding a drug; predicting the drug-response of the nerve cells on the basis of the classification result thus obtained; and sorting the nerve cells on the basis of the prediction result thus obtained.
Inventors:
AIBA KAZUHIRO (JP)
SATO HARUKA (JP)
SUDO MASAKI (JP)
SATO HARUKA (JP)
SUDO MASAKI (JP)
Application Number:
PCT/JP2020/033246
Publication Date:
March 11, 2021
Filing Date:
September 02, 2020
Export Citation:
Assignee:
STEM CELL & DEVICE LABORATORY INC (JP)
International Classes:
C12Q1/04; G01N33/48; G01N33/483
Domestic Patent References:
| WO2019087991A1 | 2019-05-09 | |||
| WO2019098256A1 | 2019-05-23 |
Foreign References:
| JP2018121567A | 2018-08-09 |
Other References:
SAKUTA, HIROMICHI, KUDOH, SUGURU N.: "An attempt of feature extraction of neuronal activity patterns in living neuronal network, by multi-layered artificial neuronal network", THE 32ND ANNUAL CONFERENCE OF THE JAPANESE SOCIETY FOR ARTIFICIAL INTELLIGENCE, 8 June 2018 (2018-06-08)
DERMUTZ, H ET AL.: "Paper-based patterned 3D neural cultures as a tool to study network activity on multielectrode array s", RSC ADVANCES, vol. 7, 11 August 2017 (2017-08-11), pages 39359 - 39371, XP055610324, DOI: 10.1039/C7RA00971B
LEE, S. ET AL.: "Fabrication of a Highly Aligned Neural Scaffold via a Table Top Stereolithography 3D Printing and Electrospinning", TISSUE ENGINEERING: PART A, vol. 23, no. 11-12, 11 January 2017 (2017-01-11), pages 491 - 502, XP009508987, DOI: 10.1089/ten.tea.2016.0353
DERMUTZ, H ET AL.: "Paper-based patterned 3D neural cultures as a tool to study network activity on multielectrode array s", RSC ADVANCES, vol. 7, 11 August 2017 (2017-08-11), pages 39359 - 39371, XP055610324, DOI: 10.1039/C7RA00971B
LEE, S. ET AL.: "Fabrication of a Highly Aligned Neural Scaffold via a Table Top Stereolithography 3D Printing and Electrospinning", TISSUE ENGINEERING: PART A, vol. 23, no. 11-12, 11 January 2017 (2017-01-11), pages 491 - 502, XP009508987, DOI: 10.1089/ten.tea.2016.0353
Attorney, Agent or Firm:
SHA PATENT AND TRADEMARK FIRM (JP)
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