Title:
METHOD FOR STABILIZING LUCIFERIN AND METHOD FOR MEASURING BIOLUMINESCENCE
Document Type and Number:
WIPO Patent Application WO/2017/057672
Kind Code:
A1
Abstract:
The problem to be solved by the present invention is to provide a composition that increases the stability of a luciferin solution. The present invention provides: a method for stabilizing a luciferin solution, said method characterized in that a boronic acid derivative or a salt thereof is made to coexist in the luciferin solution; and a method for suppressing an attenuation or a decrease in the intensity of bioluminescence, said method characterized in that, when carrying out a bioluminescence reaction of luciferase using luciferin as a substrate, a pyrophosphate and a boronic acid derivative or a salt thereof are made to coexist.
Inventors:
YAMAOKA TOSHIHIKO (JP)
Application Number:
PCT/JP2016/079006
Publication Date:
April 06, 2017
Filing Date:
September 30, 2016
Export Citation:
Assignee:
EIKEN CHEMICAL (JP)
International Classes:
C12Q1/66; G01N33/532
Domestic Patent References:
| WO1999011766A1 | 1999-03-11 |
Foreign References:
| JP2000253899A | 2000-09-19 | |||
| JP2000166550A | 2000-06-20 | |||
| JP2000319280A | 2000-11-21 | |||
| JP2014039486A | 2014-03-06 | |||
| JPH0847399A | 1996-02-20 | |||
| JPH10210999A | 1998-08-11 | |||
| JP2008092900A | 2008-04-24 |
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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