Title:
METHODS OF INHIBITING ANGIOGENESIS AND TUMOR GROWTH, AND TREATING OPHTHALMOLOGIC CONDITIONS WITH ANGIOSTATIC AND THERAPEUTIC STEROIDS
Document Type and Number:
WIPO Patent Application WO/1995/018621
Kind Code:
A1
Abstract:
Methods for treating angiogenesis, tumors, and ocular hypertension with steroids are disclosed herein. The steroids have angiostatic activity with reduced glucocorticoid activity. A preferred steroid is 6'alpha',9'alpha'-fluoro-11'beta',17-dihydroxy-16'alpha'-methyl-pregna-1,4-diene-3-one-17-carboxylic acid.
Inventors:
PETROW VLADIMIR
PROIA ALAN D
PROIA ALAN D
Application Number:
PCT/US1995/000165
Publication Date:
July 13, 1995
Filing Date:
January 04, 1995
Export Citation:
Assignee:
UNIV DUKE (US)
International Classes:
A61K31/56; A61K31/565; A61K31/57; A61K31/575; A61K31/58; A61P9/00; C07J1/00; (IPC1-7): A61K31/56; A61K31/58
Foreign References:
| US5371078A | 1994-12-06 | |||
| US4686214A | 1987-08-11 | |||
| US4617299A | 1986-10-14 | |||
| US4599331A | 1986-07-08 |
Other References:
See also references of EP 0742718A4
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