Title:
METHODS AND PHARMACEUTICAL COMPOSITION FOR TREATING DISEASES
Document Type and Number:
WIPO Patent Application WO/2022/171150
Kind Code:
A1
Abstract:
A new polymorphic form of (R) -praziquantel, the novel anhydrate (R) -2 (cyclohexanecarbonyl) -2, 3, 6, 7-tetrahydro-1H-pyrazino [2, 1-a] isoquinolin-4 (11bH), compositions comprising the polymorphic form, methods of making pharmaceutical formulations comprising the polymorphic form. Also providing improved methods of their use for controlling, treating and preventing zoonotic and parasitic diseases inhumans and animals, which comprising administering to the subject in need thereof a therapeutically effective amount of the active agent with a pharmaceutical formulation.
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Inventors:
QIAN MINGXIN (CN)
HO RODNEY (CN)
CHEN TY (CN)
HO RODNEY (CN)
CHEN TY (CN)
Application Number:
PCT/CN2022/075737
Publication Date:
August 18, 2022
Filing Date:
February 09, 2022
Export Citation:
Assignee:
TONGLI BIOMEDICAL CO LTD (CN)
International Classes:
C07D471/04; A61K9/20; A61K31/4985; A61P33/00
Foreign References:
| CN111171027A | 2020-05-19 | |||
| CN107151246A | 2017-09-12 | |||
| CN103160562A | 2013-06-19 | |||
| US20140256003A1 | 2014-09-11 | |||
| CN104327077A | 2015-02-04 | |||
| CN104127389A | 2014-11-05 |
Other References:
BAGCHUS WILHELMINA MARIA, BEZUIDENHOUT DEON, HARRISON‐MOENCH ELEANOR, KOURANY‐LEFOLL ELLY, WOLNA PETER, YALKINOGLU OEZKAN: "Relative Bioavailability of Orally Dispersible Tablet Formulations of Levo‐ and Racemic Praziquantel: Two Phase I Studies", CTS - CLINICAL AND TRANSLATIONAL SCIENCE, WILEYBLACKWELL PUB., US, vol. 12, no. 1, 1 January 2019 (2019-01-01), US , pages 66 - 76, XP055958789, ISSN: 1752-8054, DOI: 10.1111/cts.12601
Attorney, Agent or Firm:
SUZHOU CREATOR PATENT & TRADEMARK AGENCY, LTD. (CN)
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