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Title:
METHODS FOR PRODUCING D-MANNOSE ISOMERASE AND D-FRUCTOSE
Document Type and Number:
WIPO Patent Application WO/2022/149542
Kind Code:
A1
Abstract:
A problem addressed by the present invention is to provide a membrane-bound D-mannose isomerase having an optimum reaction pH in the acidic region. Membrane-bound D-mannose isomerase derived from acetic acid bacteria is produced. The acetic acid bacteria preferably belong to the genus Acetobacter, Gluconobacter, or Gluconacetobacter. Also, fructose is produced from D-mannose using the membrane-bound D-mannose isomerase derived from acetic acid bacteria.

Inventors:
ADACHI OSAO (JP)
YAKUSHI TOSHIHARU (JP)
KATAOKA NAOYA (JP)
MATSUSHITA KAZUNOBU (JP)
Application Number:
PCT/JP2021/048791
Publication Date:
July 14, 2022
Filing Date:
December 28, 2021
Export Citation:
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Assignee:
UNIV YAMAGUCHI (JP)
International Classes:
C12N9/90; C12N11/02; C12P19/02
Domestic Patent References:
WO2008062569A12008-05-29
WO2000065072A12000-11-02
Foreign References:
US4734366A1988-03-29
Other References:
OSAO ADACHI, NAOYA KATAOKA, KAZUNOBU MATSUSHITA, YOSHIHIKO AKAKABE, TOSHIHARUYAKUSHI: "4C01-13 Discovery of membrane-bound D-mannose isomerase and its application to high fructose syrup production", ANNUAL MEETING OF THE JAPAN SOCIETY FOR BIOSCIENCE, 5 March 2021 (2021-03-05) - 18 March 2021 (2021-03-18), JP , pages 1123 - 1123, XP009538080, ISSN: 2186-7976
AMEYAMA ET AL., J. BACTERIOL, vol. 145, 1981, pages 814 - 23
YAMANAKA K.IZUMORI K., METHODS IN ENZYMOL., vol. 41, 1975, pages 462 - 465
ADACHI ET AL., AGRIC. BIOL. CHEM., vol. 44, 1980, pages 301 - 308
Attorney, Agent or Firm:
FUJIMOTO Shohei (JP)
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