MICROORGANISM WITH ENHANCED ACTIVITY OF ASPARTATE 1-DECARBOXYLASE DERIVED FROM TRIBOLIUM CASTANEUM, AND USES THEREOF

Title:

MICROORGANISM WITH ENHANCED ACTIVITY OF ASPARTATE 1-DECARBOXYLASE DERIVED FROM TRIBOLIUM CASTANEUM, AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2023/177254

Kind Code:

A1

Abstract:

The present application provides: a microorganism with enhanced activity of aspartate 1-decarboxylase derived from Tribolium castaneum; a composition for producing beta-alanine and/or a beta-alanine-derived compound, the composition comprising the microorganism; and a method for producing beta-alanine and/or a beta-alanine-derived compound, the method comprising a step for culturing the microorganism. The productivity of beta-alanine and/or a beta-alanine-derived compound is excellent.

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Inventors:

JANG YEON-JAE (KR)
SHIN KWANG SOO (KR)
SO YEE-SEUL (KR)
LEE KWANG WOO (KR)

Application Number:

PCT/KR2023/003573

Publication Date:

September 21, 2023

Filing Date:

March 17, 2023

Export Citation:

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Assignee:

CJ CHEILJEDANG CORP (KR)

International Classes:

C12N1/20; C12N9/88; C12N15/77; C12P13/06; C12R1/15

Domestic Patent References:

WO2020005834A1

2020-01-02

Foreign References:

KR20160112783A	2016-09-28
CN112625985A	2021-04-09

Other References:

YU XIN-JUN, HUANG CHANG-YI, XU XIAO-DAN, CHEN HONG, LIANG MIAO-JIE, XU ZHE-XIAN, XU HUI-XIA, WANG ZHAO: "Protein Engineering of a Pyridoxal-5′-Phosphate-Dependent l-Aspartate-α-Decarboxylase from Tribolium castaneum for β-Alanine Production", MOLECULES, vol. 25, no. 6, pages 1280, XP055965048, DOI: 10.3390/molecules25061280
WANG LEI; PIAO XIAOYU; CUI SHUMEI; HU MEIRONG; TAO YONG: "Enhanced production of β-alanine through co-expressing two different subtypes of-aspartate-α-decarboxylase", JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, BASINGSTOKE, GB, vol. 47, no. 6-7, 10 June 2020 (2020-06-10), GB , pages 465 - 474, XP037200448, ISSN: 1367-5435, DOI: 10.1007/s10295-020-02285-5

Attorney, Agent or Firm:

YOU ME PATENT AND LAW FIRM (KR)

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