Title:
MITOCHONDRIAL FUNCTION ACTIVATOR
Document Type and Number:
WIPO Patent Application WO/2020/262114
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a pharmaceutical agent which activates mitochondrial function, particularly, an inexpensive pharmaceutical agent. The problem can be solved by a mitochondrial function activator of the present invention containing β-alanine or glycine, or a salt thereof.
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Inventors:
NODA TETSUJI (JP)
ONAGA TOMOTSUNE (JP)
KATAKURA YOSHINORI (JP)
ONAGA TOMOTSUNE (JP)
KATAKURA YOSHINORI (JP)
Application Number:
PCT/JP2020/023600
Publication Date:
December 30, 2020
Filing Date:
June 16, 2020
Export Citation:
Assignee:
YUKI GOSEI YAKUHIN KOGYO KK (JP)
UNIV KYUSHU NAT UNIV CORP (JP)
UNIV KYUSHU NAT UNIV CORP (JP)
International Classes:
A61P3/00; A23L33/175; A61K31/197; A61K31/198; A61P3/04; A61P9/00; A61P9/04; A61P9/10; A61P13/12; A61P21/00; A61P21/06; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P35/00; A61P43/00
Foreign References:
| JP2015097507A | 2015-05-28 | |||
| JP2015097507A | 2015-05-28 | |||
| JP2014162792A | 2014-09-08 |
Other References:
HEIDARI, R. ET AL.: "Mitochondria protection as a mechanism underlying the hepatoprotective effects of glycine in cholestatic mice", BIOMEDICINE AND PHARMACOTHERAPY, vol. 97, 2018, pages 1086 - 1095, XP085323849, ISSN: 0753-3322, DOI: 10.1016/j.biopha.2017.10.166
TALLON M J : "The therapeutic potential of oral beta-alanine supplementation", AGRO FOOD INDUSTRY HI-TECH., vol. 19, no. 5, 2008, pages 58 - 59, XP009532969, ISSN: 1722-6996
MURAKAMI, T. ET AL.: "The impact of taurine- and beta-alanine-supplemented diets on behavioral and neurochemical parameters in mice: antidepressant versus anxiolytic-like effects", AMINO ACIDS, vol. 39, 2010, pages 427 - 434, XP019853778, ISSN: 1438-2199
HOFFMAN, J. R. ET AL.: "beta-Alanine supplemented diets enhance behavioral resilience to stress exposure in an animal model of PTSD", AMINO ACIDS, vol. 47, 2015, pages 1247 - 1257, XP035811072, ISSN: 1438-2199
FORD, ORG. SYS. COLL., vol. 3, 1955, pages 34
TALLON M J : "The therapeutic potential of oral beta-alanine supplementation", AGRO FOOD INDUSTRY HI-TECH., vol. 19, no. 5, 2008, pages 58 - 59, XP009532969, ISSN: 1722-6996
MURAKAMI, T. ET AL.: "The impact of taurine- and beta-alanine-supplemented diets on behavioral and neurochemical parameters in mice: antidepressant versus anxiolytic-like effects", AMINO ACIDS, vol. 39, 2010, pages 427 - 434, XP019853778, ISSN: 1438-2199
HOFFMAN, J. R. ET AL.: "beta-Alanine supplemented diets enhance behavioral resilience to stress exposure in an animal model of PTSD", AMINO ACIDS, vol. 47, 2015, pages 1247 - 1257, XP035811072, ISSN: 1438-2199
FORD, ORG. SYS. COLL., vol. 3, 1955, pages 34
Attorney, Agent or Firm:
YAMAGUCHI Kenjiro et al. (JP)
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