Title:
MODIFIED GAMMA-CARBON SKELETON COMPOUND AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2021/133032
Kind Code:
A1
Abstract:
The present invention provides a modified gamma-carbon skeleton compound and a method for preparing same. The modified gamma-carbon skeleton compound of the present invention can produce a peptide nucleic acid monomer with high yield and purity by introducing a functional group having a controlled specific protecting group, thus enabling the mass production of peptide nucleic acid oligomers.
Inventors:
PARK HEE KYUNG (KR)
KIM YONGTAE (KR)
JEON JUHYEON (KR)
JUNG JINWOO (KR)
SUH BYOUNG WOO (KR)
HONG IN SEOK (KR)
KIM YONGTAE (KR)
JEON JUHYEON (KR)
JUNG JINWOO (KR)
SUH BYOUNG WOO (KR)
HONG IN SEOK (KR)
Application Number:
PCT/KR2020/018907
Publication Date:
July 01, 2021
Filing Date:
December 22, 2020
Export Citation:
Assignee:
SEASUNBIO MAT (KR)
International Classes:
C07K14/00; C07K1/06
Domestic Patent References:
WO2012138955A2 | 2012-10-11 |
Foreign References:
KR20190139890A | 2019-12-18 | |||
KR20030042180A | 2003-05-28 | |||
KR20030084444A | 2003-11-01 |
Other References:
ENGLUND ETHAN A; APPELLA DANIEL H: "Synthesis of gamma-substituted peptide nucleic acids: A new place to attach fluorophores without affecting DNA binding", ORGANIC LETTERS, vol. 7, no. 16, 1 August 2005 (2005-08-01), US, pages 3465 - 3467, XP008144826, ISSN: 1523-7060
Attorney, Agent or Firm:
PLUS INTERNATIONAL IP LAW FIRM (KR)
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