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Title:
MODIFIED PROMOTER, EXPRESSION VECTOR, MICROORGANISM, PRODUCTION METHOD FOR SUBSTANCE, MODIFIED CYANOBACTERIA, AND MANUFACTURING METHOD FOR MODIFIED PROMOTER
Document Type and Number:
WIPO Patent Application WO/2023/233996
Kind Code:
A1
Abstract:
The present disclosure provides a modified promoter capable of flexibly regulating the expression level of a gene encoding a protein. The modified promoter according to the present disclosure is a promoter modified by, with respect to a 348-nucleotide nucleotide sequence (sequence number 1) upstream of an initiator codon of an slr1841 gene, or a nucleotide sequence having not less than 80% homology with the nucleotide sequence represented by sequence number 1, performing at least one selected from the group consisting of (i) substituting another nucleotide for one or more nucleotides included in the nucleotide sequence, (ii) deleting one or more nucleotides from the nucleotide sequence, and (iii) inserting one or more nucleotides into the nucleotide sequence.

Inventors:
WAKABAYASHI MASAYA
KUSAMA SHOKO
KOJIMA SEIJI
Application Number:
PCT/JP2023/018190
Publication Date:
December 07, 2023
Filing Date:
May 16, 2023
Export Citation:
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Assignee:
PANASONIC IP MAN CO LTD (JP)
International Classes:
C12N15/11; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63; C12P1/04
Domestic Patent References:
WO2021100640A12021-05-27
Foreign References:
JP2003519492A2003-06-24
JP2006513692A2006-04-27
Other References:
DATABASE Nucleotide 6 February 2020 (2020-02-06), "Synechocystis sp. CACIAM 05, complete genome", Database accession no. CP019225.1
DATABASE Nucleotide 5 May 2021 (2021-05-05), "Synechocystis sp. PCC 7338 chromosome, complete genome", Database accession no. CP054306.1
DATABASE Nucleotide 11 April 2022 (2022-04-11), "Synechocystis sp. PCC 6803 substr. GT-T chromosome, complete genome", Database accession no. CP094998.1
Attorney, Agent or Firm:
KAMATA Kenji et al. (JP)
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