Title:
MOLECULAR MARKER DETECTION AND REGULATING METHODS IN DE-SERVITIZATION STATE OF CELLS
Document Type and Number:
WIPO Patent Application WO/2020/211841
Kind Code:
A1
Abstract:
The present invention provides a use for a small nucleolar RNA (snoRNA) or a detection reagent thereof, for use in detection of a servitization state of cells; moreover, detection and regulating methods for the snoRNA are established.
Inventors:
ZHANG CHENYU (CN)
ZHOU ZHEN (CN)
HU XIUTING (CN)
LI JING (CN)
ZHOU XINYAN (CN)
ZHOU ZHEN (CN)
HU XIUTING (CN)
LI JING (CN)
ZHOU XINYAN (CN)
Application Number:
PCT/CN2020/085364
Publication Date:
October 22, 2020
Filing Date:
April 17, 2020
Export Citation:
Assignee:
UNIV NANJING (CN)
International Classes:
C12Q1/68
Domestic Patent References:
| WO2011036091A1 | 2011-03-31 |
Foreign References:
| CN104894259A | 2015-09-09 |
Other References:
CUOMOD ET AL.: "Transcriptional Landscape of Mouse-Aged Ovaries Reveals a Unique Set of Non-coding RNAs Associated with Physiological and Environmental Ovarian Dysfunctions", CELL DEATH DISCOVERY, vol. 4, no. 112, 5 December 2018 (2018-12-05), XP055746051
CUOMOD ET AL.: "Transcriptional Landscape of Mouse-Aged Ovaries Reveals a Unique Set of Non-coding RNAs Associated with Physiological and Environmental Ovarian Dysfunctions", CELL DEATH DISCOVERY, vol. 4, 5 December 2018 (2018-12-05), XP055746051
ZHANG, XIAOCHEN ET AL.: "Structure and Function of snoRNAs", CHINESE BULLETIN OF LIFE SCIENCES, vol. 20, no. 2, 30 April 2008 (2008-04-30), XP055746065
SAMBROOK ET AL.: "Molecular Cloning: Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
See also references of EP 3943609A4
CUOMOD ET AL.: "Transcriptional Landscape of Mouse-Aged Ovaries Reveals a Unique Set of Non-coding RNAs Associated with Physiological and Environmental Ovarian Dysfunctions", CELL DEATH DISCOVERY, vol. 4, 5 December 2018 (2018-12-05), XP055746051
ZHANG, XIAOCHEN ET AL.: "Structure and Function of snoRNAs", CHINESE BULLETIN OF LIFE SCIENCES, vol. 20, no. 2, 30 April 2008 (2008-04-30), XP055746065
SAMBROOK ET AL.: "Molecular Cloning: Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
See also references of EP 3943609A4
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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