Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
NALIDINONE COMPOUND AS FGFR4 INHIBITOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/060904
Kind Code:
A1
Abstract:
Disclosed is a 2-oxo-1,2-dihydro-1,6-naphthyridin-7-yl compound, which is a compound having a structure as shown in formula (I), a stereoisomer thereof, a tautomer thereof, or a pharmaceutically acceptable salt thereof; R1 is selected from one or more of a halogen or a C1-C6 alkoxy group; R2 is -(CH2)nNR3R4 or -(CH2)nOH, n being 2 or 3; R3 and R4 are independently selected from alkyl groups, or R3 and R4 are combined with an N atom connecting R3 and R4 to form a 5-6 membered ring group. The compound can selectively inhibit FGFR4, and can be used as a potential antitumor drug.

More Like This:
JP5095216Arylimidazole and its use as an anticancer agent
WO/2018/127130COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS
JP6190076Use as complex aromatic compounds and its dopamine D1 ligand
Inventors:
LI XIAOKUN (CN)
LIU ZHIGUO (CN)
ZHEN XIAOHUI (CN)
LIN LI (CN)
QIAN JIANCHANG (CN)
Application Number:
PCT/CN2022/095973
Publication Date:
April 20, 2023
Filing Date:
May 30, 2022
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
UNIV WENZHOU MEDICAL (CN)
International Classes:
C07D471/04; A61P35/00
Domestic Patent References:
WO2018113584A12018-06-28
Foreign References:
CN113912602A2022-01-11
CN109745325A2019-05-14
CN108264511A2018-07-10
CN105307657A2016-02-03
CN109384790A2019-02-26
CN104540809A2015-04-22
Attorney, Agent or Firm:
HANGZHOU ZHIXIAN PATENT AGENCY (CN)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: CONSTRUCTION METHOD FOR REGIONAL ECONOMIC DEVELOPMENT QUALITY EVALUATION MODEL BASED ON ELECTRIC POW...

Next Patent: COVER FOR CONDENSER OF CLOTHING TREATING APPARATUS, AND CLOTHING TREATING APPARATUS