Title:
NANODISC COMPRISING ANGIOTENSIN CONVERTING ENZYME 2
Document Type and Number:
WIPO Patent Application WO/2023/158159
Kind Code:
A1
Abstract:
The present invention relates to a nanodisc comprising angiotensin converting enzyme 2 (ACE2) and a membrane scaffold protein (MSP). In the present invention, the angiotensin converting enzyme 2 (ACE2) is included in the nanodisc, and it was confirmed that the antiviral efficacy and substrate converting ability of the angiotensin converting enzyme 2 (ACE2) could be significantly improved.
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Inventors:
KWEON DAE HYUK (KR)
HWANG JAE HYEON (KR)
KIM KYEONG WON (KR)
YOON JEONG HYEON (KR)
PARK WON BEOM (KR)
HWANG JAE HYEON (KR)
KIM KYEONG WON (KR)
YOON JEONG HYEON (KR)
PARK WON BEOM (KR)
Application Number:
PCT/KR2023/001967
Publication Date:
August 24, 2023
Filing Date:
February 10, 2023
Export Citation:
Assignee:
MVRIX CO LTD (KR)
RESEARCH ＆ BUSINESS FOUNDATION SUNGKYUNKWAN UNIV (KR)
RESEARCH ＆ BUSINESS FOUNDATION SUNGKYUNKWAN UNIV (KR)
International Classes:
A61K9/127; A23L33/17; A61K38/48; A61P9/00
Domestic Patent References:
| WO2021078786A1 | 2021-04-29 |
Foreign References:
| US11053301B2 | 2021-07-06 | |||
| KR102181991B1 | 2020-11-23 | |||
| KR101994279B1 | 2019-06-28 | |||
| KR102438721B1 | 2022-08-31 |
Other References:
JAEHYEON HWANG, KYEONG WON KIM, JEONG HYEON YOON, WONBEOM PARK, YOUNGSEO PARK, SU-HYUN KIM, DAE-HYUK KWEON : " Development of ACE2-embedded Nanodisc as Broad-spectrum Antivirals against SARS-related Coronaviruses. ", 28 September 2022 (2022-09-28) - 30 September 2022 (2022-09-30), pages 147, XP009548218
Attorney, Agent or Firm:
TAEDONG PATENT & LAW FIRM (KR)
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