Title:
NANOPARTICLES COMPRISING ENZYME-BASED GOLD NANOCLUSTERS, AND METHOD FOR MANUFACTURING SAME
Document Type and Number:
WIPO Patent Application WO/2022/080543
Kind Code:
A1
Abstract:
The present invention relates to nanoparticles comprising enzyme-based gold nanoclusters and to a method for manufacturing same, the nanoparticles being formed by the agglomeration of protein-gold nanoclusters and enzyme-gold nanoclusters, and thus being capable of improving stability and sensing sensitivity.
Inventors:
OH BYUNG KEUN (KR)
LEE MYEONG JUN (KR)
SHIN JEONG HYEOP (KR)
SONG JI AE (KR)
KIM TAE HWAN (KR)
LEE SANG NAM (KR)
LEE MYEONG JUN (KR)
SHIN JEONG HYEOP (KR)
SONG JI AE (KR)
KIM TAE HWAN (KR)
LEE SANG NAM (KR)
Application Number:
PCT/KR2020/014347
Publication Date:
April 21, 2022
Filing Date:
October 20, 2020
Export Citation:
Assignee:
UNIV SOGANG RES FOUNDATION (KR)
UNIANCE GENE (KR)
UNIANCE GENE (KR)
International Classes:
C12N11/14; C12Q1/28; C12Q1/54; B82Y15/00
Foreign References:
| KR20180048422A | 2018-05-10 |
Other References:
LEE MYEONG-JUN, LEE EUN-SOL, KIM TAE-HWAN, JEON JU-WON, KIM YONGTAE, OH BYUNG-KEUN: "Detection of thioredoxin-1 using ultra-sensitive ELISA with enzyme-encapsulated human serum albumin nanoparticle", NANO CONVERGENCE, vol. 6, no. 1, 1 December 2019 (2019-12-01), XP055922150, DOI: 10.1186/s40580-019-0210-5
OH, BYEONG GEUN: "Development of Nano Capsule, a Bio-Optimized Protein with Cancer Synergistic Treatment Function", GOVERNMENT PROJECT FINAL REPORT, SOGANG UNIVERSITY, KOREA, 1 January 2018 (2018-01-01), Korea, pages 1 - 40, XP009536309
OH, BYEONG GEUN: "A New Albumin Nanocomposite including Short Interference RNA and Gold Nanorods that Maximize Anticancer Treatment Effects", BT NEWS, KOREA, vol. 23, no. 2, 1 January 2016 (2016-01-01), Korea, pages 35 - 39, XP009536004, ISSN: 1738-2335
CHI JINGTIAN, GUO MANLI, ZHANG CHI, ZHANG YUANHONG, AI SHIYUN, HOU JUYING, WU PENG, LI XIANGYANG: "Glucose oxidase and Au nanocluster co-encapsulated metal–organic frameworks as a sensitive colorimetric sensor for glucose based on a cascade reaction", NEW JOURNAL OF CHEMISTRY, ROYAL SOCIETY OF CHEMISTRY, GB, vol. 44, no. 31, 10 August 2020 (2020-08-10), GB , pages 13344 - 13349, XP055922154, ISSN: 1144-0546, DOI: 10.1039/C9NJ06339K
OH, BYEONG GEUN: "Development of Nano Capsule, a Bio-Optimized Protein with Cancer Synergistic Treatment Function", GOVERNMENT PROJECT FINAL REPORT, SOGANG UNIVERSITY, KOREA, 1 January 2018 (2018-01-01), Korea, pages 1 - 40, XP009536309
OH, BYEONG GEUN: "A New Albumin Nanocomposite including Short Interference RNA and Gold Nanorods that Maximize Anticancer Treatment Effects", BT NEWS, KOREA, vol. 23, no. 2, 1 January 2016 (2016-01-01), Korea, pages 35 - 39, XP009536004, ISSN: 1738-2335
CHI JINGTIAN, GUO MANLI, ZHANG CHI, ZHANG YUANHONG, AI SHIYUN, HOU JUYING, WU PENG, LI XIANGYANG: "Glucose oxidase and Au nanocluster co-encapsulated metal–organic frameworks as a sensitive colorimetric sensor for glucose based on a cascade reaction", NEW JOURNAL OF CHEMISTRY, ROYAL SOCIETY OF CHEMISTRY, GB, vol. 44, no. 31, 10 August 2020 (2020-08-10), GB , pages 13344 - 13349, XP055922154, ISSN: 1144-0546, DOI: 10.1039/C9NJ06339K
Attorney, Agent or Firm:
KIM, Hyun Jin (KR)
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