Title:
NAPHTHALENE RING-CONTAINING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/237904
Kind Code:
A1
Abstract:
A naphthalene ring-containing compound, a pharmaceutical composition containing same, and the use thereof. A naphthalene ring-containing compound as represented by formula III, a pharmaceutically acceptable salt thereof, a solvate thereof, or a solvate of the pharmaceutically acceptable salt thereof. The compound is new in structure and has a better activity on cancers.
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Inventors:
WU LIANG (CN)
DENG YIJUN (CN)
HE ZHENHUA (CN)
SUN QIAOLING (CN)
ZHOU CHEN (CN)
WANG TIELIN (CN)
DENG YIJUN (CN)
HE ZHENHUA (CN)
SUN QIAOLING (CN)
ZHOU CHEN (CN)
WANG TIELIN (CN)
Application Number:
PCT/CN2022/092865
Publication Date:
November 17, 2022
Filing Date:
May 13, 2022
Export Citation:
Assignee:
JIANGSU YAHONG MEDITECH CO LTD (CN)
ASIERIS PHARMACEUTICALS SHANGHAI CO LTD (CN)
ASIERIS PHARMACEUTICALS SHANGHAI CO LTD (CN)
International Classes:
C07C35/36; A61K31/165; A61P35/00; C07C233/64; C07C309/29
Domestic Patent References:
| WO2005073205A1 | 2005-08-11 | |||
| WO2019241231A1 | 2019-12-19 | |||
| WO2020142227A1 | 2020-07-09 |
Foreign References:
| CN110612297A | 2019-12-24 | |||
| CN1668303A | 2005-09-14 | |||
| CN202110533784A | 2021-05-14 | |||
| CN202210506641A | 2022-05-05 |
Other References:
BENOWITZ ANDREW B., JONES KATHERINE L., HARLING JOHN D.: "The therapeutic potential of PROTACs", EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 31, no. 1, 2 January 2021 (2021-01-02), GB , pages 1 - 24, XP093005387, ISSN: 1354-3776, DOI: 10.1080/13543776.2021.1840553
JIANTAO HU, BIAO HU, MINGLIANG WANG, FUMING XU, BUKEYAN MIAO, CHAO-YIE YANG, MI WANG, ZHAOMIN LIU, DANIEL F. HAYES, KRISHNAPRIYA C: "Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER)", JOURNAL OF MEDICINAL CHEMISTRY, vol. 62, no. 3, 14 February 2019 (2019-02-14), US , pages 1420 - 1442, XP055672912, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.8b01572
"Pharmacopoeia of the People's Republic of China", 2020
RAYMOND C ROWE, HANDBOOK OF PHARMACEUTICAL EXCIPIENTS, 2009
JIANTAO HU, BIAO HU, MINGLIANG WANG, FUMING XU, BUKEYAN MIAO, CHAO-YIE YANG, MI WANG, ZHAOMIN LIU, DANIEL F. HAYES, KRISHNAPRIYA C: "Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER)", JOURNAL OF MEDICINAL CHEMISTRY, vol. 62, no. 3, 14 February 2019 (2019-02-14), US , pages 1420 - 1442, XP055672912, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.8b01572
"Pharmacopoeia of the People's Republic of China", 2020
RAYMOND C ROWE, HANDBOOK OF PHARMACEUTICAL EXCIPIENTS, 2009
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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