Title:
NEURITE ELONGATION INDUCING AGENT
Document Type and Number:
WIPO Patent Application WO/2005/097155
Kind Code:
A1
Abstract:
Exhibiting a high neurite elongation effect, a novel neurite elongation agent, therapeutic or preventive agent for neurodegenerative disorder, food or drink for the treatment or prevention of this disorder, method of inducing neurite elongation, method of treating or preventing neurological disorder, method of enhancing or improving learning and/or memorizing capacity, use of sugar chain in the production of medicine for the treatment or prevention of neurological disorder, and use of sugar chain in the production of learning and/or memorizing capacity enhancer or improver.
Inventors:
GU JIANGUO (JP)
SHIGETA MASAKI (JP)
TANIGUCHI NAOYUKI (JP)
SHIGETA MASAKI (JP)
TANIGUCHI NAOYUKI (JP)
Application Number:
PCT/JP2005/006640
Publication Date:
October 20, 2005
Filing Date:
April 05, 2005
Export Citation:
Assignee:
TAKARA BIO INC (JP)
GU JIANGUO (JP)
SHIGETA MASAKI (JP)
TANIGUCHI NAOYUKI (JP)
GU JIANGUO (JP)
SHIGETA MASAKI (JP)
TANIGUCHI NAOYUKI (JP)
International Classes:
A61K38/00; A61K48/00; A61P25/00; A61P25/14; A61P25/16; A61P25/28; (IPC1-7): A61K38/00; A61K48/00; A61P25/00; A61P25/14; A61P25/16; A61P25/28
Foreign References:
| JPH07126185A | 1995-05-16 |
Other References:
ZAMZE S. ET AL.: "A family of novel, acidic N-glycans in Bowes Melanoma tissue plasminogen activator have L2/HNK-1-bearing antennae, many with sulfation of the fucosylated chitobiose core.", EUR. J.BIOCHEM., vol. 268, no. 14, 2001, pages 4063 - 4078, XP002994502
VOSHOL H. ET AL.: "Structure of the HNK-1 carbohydrate epitope ons peripheral myelin glycoprotein.", J.BIOL.CHEM., vol. 271, no. 38, 1996, pages 22957 - 22560, XP002138942
YAZAKI T. ET AL.: "Peripheral myelin p0 protein mediates neurite outgrowth of cortical neurons in vitro and axonal regeneration in vivo.", NEUROSCI.LETT., vol. 176, no. 1, 1994, pages 13 - 16, XP002994503
GU J. ET AL.: "beta1,4-N-Acetylglucosaminyl transferese III down-regulates neurite outgrowth induced by costimulation of epidermal growth factor and integrins through the Ras/ERK signaling pathway in PC12 cells.", GLYCOBIOLOGY, vol. 14, no. 2, February 2004 (2004-02-01), pages 177 - 186, XP002994504
VOSHOL H. ET AL.: "Structure of the HNK-1 carbohydrate epitope ons peripheral myelin glycoprotein.", J.BIOL.CHEM., vol. 271, no. 38, 1996, pages 22957 - 22560, XP002138942
YAZAKI T. ET AL.: "Peripheral myelin p0 protein mediates neurite outgrowth of cortical neurons in vitro and axonal regeneration in vivo.", NEUROSCI.LETT., vol. 176, no. 1, 1994, pages 13 - 16, XP002994503
GU J. ET AL.: "beta1,4-N-Acetylglucosaminyl transferese III down-regulates neurite outgrowth induced by costimulation of epidermal growth factor and integrins through the Ras/ERK signaling pathway in PC12 cells.", GLYCOBIOLOGY, vol. 14, no. 2, February 2004 (2004-02-01), pages 177 - 186, XP002994504
Attorney, Agent or Firm:
Hosoda, Yoshinori c/o Hosoda International Patent Office (P.O. Box 26 OMM Building 5th Floor, 7-31,
Otemae 1-chome, Chuo-k, Osaka-shi Osaka 91, JP)
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