NEW USES OF RIFAMYCIN-QUINOLIZIDONE DUAL-TARGET MOLECULES

Title:

NEW USES OF RIFAMYCIN-QUINOLIZIDONE DUAL-TARGET MOLECULES

Document Type and Number:

WIPO Patent Application WO/2018/157749

Kind Code:

A8

Abstract:

Applications of rifamycin-quinolizidone dual-target molecules represented in formula I in inhibition of ammonia production floras in a gastrointestinal tract. The rifamycin-quinolizidone dual-target molecules represented in formula I are similar to an antibacterial spectrum of rifaximin and have an antibacterial activity to common ammonia production floras in the gastrointestinal tract; and meanwhile, the rifamycin-quinolizidone dual-target molecules have the property of a low drug resistance frequency and have application prospects in prevention and treatment of infection of hepatic encephalopathy.

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Inventors:

MA ZHENKUN (CN)
YUAN YING (CN)
LIU YU (CN)
WANG XIAOMEI (CN)

Application Number:

PCT/CN2018/076968

Publication Date:

March 30, 2023

Filing Date:

February 22, 2018

Export Citation:

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Assignee:

TENNOR THERAPEUTICS LTD (CN)

International Classes:

A61K31/4545; A61K9/00; A61P31/04

Attorney, Agent or Firm:

JIANG SU SUNDY LAW FIRM (CN)

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