NEW APPLICATIONS OF RIFAMYCIN-NITROIMIDAZOLE COUPLING MOLECULES

Title:

NEW APPLICATIONS OF RIFAMYCIN-NITROIMIDAZOLE COUPLING MOLECULES

Document Type and Number:

WIPO Patent Application WO/2018/157750

Kind Code:

A1

Abstract:

Disclosed in the present invention are applications of rifamycin-nitroimidazole coupling molecules represented in formula (I) of the present invention in restraining anaerobic floras. The rifamycin-nitroimidazole coupling molecules represented in formula (I) of the present invention have a broad-spectrum antibacterial activity to anaerobion, have an activity to most pathogenic bacteria related to bacterial vaginosis, have a better in-vitro antimicrobial activity than that of bacterial vaginosis drugs such as metronidazole and clindamycin, and have an excellent application prospect in preventing and treating the bacterial vaginosis caused by the anaerobion or the other related diseases.

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Inventors:

MA ZHENKUN (CN)
YUAN YING (CN)
LIU YU (CN)
WANG XIAOMEI (CN)

Application Number:

PCT/CN2018/076969

Publication Date:

September 07, 2018

Filing Date:

February 22, 2018

Export Citation:

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Assignee:

TENNOR THERAPEUTICS LTD (CN)

International Classes:

A61K31/438; A61K47/54; A61P15/02; A61P31/04

Domestic Patent References:

WO2008008480A2

2008-01-17

Foreign References:

CN106860451A	2017-06-20
CN104971061A	2015-10-14
CN105037389A	2015-11-11
US7678791B2	2010-03-16

Other References: