Title:
NON-PEPTIDIC CYCLOPHILIN BINDING COMPOUNDS AND THEIR USE
Document Type and Number:
WIPO Patent Application WO2002094745
Kind Code:
A3
Abstract:
This invention relates to pharmaceutical compositions and methods of using non-peptidic cyclophilin-binding compounds in medical conditions involving breakdown of mitochondrial energy metabolism induced by calcium overload, in treating alopecia and promoting hair growth, in treating infections with filarial and helmintic parasites, and in treating and preventing infections with the human immunodeficiency virus.
Inventors:
STEINER JOSEPH P (US)
HAMILTON GREGORY S (US)
HAMILTON GREGORY S (US)
Application Number:
PCT/US2002/015359
Publication Date:
October 16, 2003
Filing Date:
May 16, 2002
Export Citation:
Assignee:
GUILFORD PHARM INC (US)
STEINER JOSEPH P (US)
HAMILTON GREGORY S (US)
STEINER JOSEPH P (US)
HAMILTON GREGORY S (US)
International Classes:
A61K8/42; A61K8/46; A61K8/49; A61K8/69; A61K31/167; A61K31/17; A61K31/18; A61K31/422; A61K31/497; A61K31/522; A61K31/555; A61K33/243; A61K45/06; A61Q7/00; (IPC1-7): A01N43/24; A01N47/28; A01N47/40; A01N47/10; A61K31/27; A61K31/275; A61K31/175; A61K31/17
Domestic Patent References:
| WO2001017953A1 | 2001-03-15 |
Other References:
See also references of EP 1401791A4
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