Title:
NON-SYMMETRIC TRIPYRRANNES IN THE SYNTHESIS OF NOVEL MACROCYCLES
Document Type and Number:
WIPO Patent Application WO2002017925
Kind Code:
A8
Abstract:
The present invention provides certain non-symmetric tripyrranes; that is, tripyrranes that do not contain a mirror plane of symmetry perpendicular to the plane containing the tripyrrane. Further, the invention includes texaphyrin compounds and sapphyrin compounds, as well as other polypyrrolic macrocycles, prepared using tripyrranes of Formula (I) as a precursor. These macrocycles are characterized by tripyrrolic portion of the macrocyclic ring having substituents that cause the heterocycle to lack a plane of symmetric perpendicular to the plane of the macrocycle.
Inventors:
MODY TARAK (US)
GALANTER JOSHUA (US)
GALANTER JOSHUA (US)
Application Number:
PCT/US2001/026755
Publication Date:
September 12, 2002
Filing Date:
August 28, 2001
Export Citation:
Assignee:
PHARMACYCLICS INC (US)
MODY TARAK (US)
GALANTER JOSHUA (US)
MODY TARAK (US)
GALANTER JOSHUA (US)
International Classes:
A61K41/00; C07D207/333; C07D207/335; C07D207/337; C07D207/34; C07D487/22; C07D207/32; (IPC1-7): A61K31/555; C07D207/00; C07D225/00; C07D245/00; C07D487/00
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