Title:
NOVEL ATP PHOSPHORIBOSYLTRANSFERASE VARIANT, AND METHOD FOR PRODUCING L-VALINE USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/163923
Kind Code:
A1
Abstract:
The present application relates to a novel ATP phosphoribosyltransferase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
Inventors:
BAE JEE YEON (KR)
KIM SEON HYE (KR)
PARK GOUN (KR)
YOON BYOUNG HOON (KR)
KIM HYO JIN (KR)
KIM HYUNG JOON (KR)
KIM SEON HYE (KR)
PARK GOUN (KR)
YOON BYOUNG HOON (KR)
KIM HYO JIN (KR)
KIM HYUNG JOON (KR)
Application Number:
PCT/KR2021/004517
Publication Date:
August 04, 2022
Filing Date:
April 09, 2021
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12N9/10; C12N15/70; C12P13/08
Foreign References:
| KR101117022B1 | 2012-03-16 | |||
| KR900007948A | 1990-06-02 | |||
| KR20150143699A | 2015-12-23 | |||
| US8465962B2 | 2013-06-18 | |||
| US7662943B2 | 2010-02-16 | |||
| US10584338B2 | 2020-03-10 | |||
| US10273491B2 | 2019-04-30 |
Other References:
DATABASE Protein 29 June 2021 (2021-06-29), ANONYMOUS: "MULTISPECIES: ATP phosphoribosyltransferase [Corynebacterium]", XP055946410, retrieved from Genbank Database accession no. WP_003860009
ROBERT K KULIS-HORN; MARCUS PERSICKE; JÖRN KALINOWSKI: "Corynebacterium glutamicum ATP-phosphoribosyl transferases suitable for l-histidine production - Strategies for the elimination of feedback inhibition", JOURNAL OF BIOTECHNOLOGY, vol. 206, 20 July 2015 (2015-07-20), Amsterdam NL , pages 26 - 37, XP055586496, ISSN: 0168-1656, DOI: 10.1016/j.jbiotec.2015.04.001
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET, vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
GENE, vol. 145, 1994, pages 69 - 73
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
"NCBI", Database accession no. WP _074495858.1
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N. ET AL.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI, vol. 15, no. 2, 2014, pages 2773 - 2793, XP055376889, DOI: 10.3390/ijms15022773
SAMBROOK ET AL., MOLECULAR CLONING, 2012
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, no. 1, 1986
SITNICKA ET AL.: "Functional Analysis of Genes", ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
"Manual of Methods for General Bacteriology", 1981, AMERICAN SOCIETY FOR BACTERIOLOGY
ROBERT K KULIS-HORN; MARCUS PERSICKE; JÖRN KALINOWSKI: "Corynebacterium glutamicum ATP-phosphoribosyl transferases suitable for l-histidine production - Strategies for the elimination of feedback inhibition", JOURNAL OF BIOTECHNOLOGY, vol. 206, 20 July 2015 (2015-07-20), Amsterdam NL , pages 26 - 37, XP055586496, ISSN: 0168-1656, DOI: 10.1016/j.jbiotec.2015.04.001
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET, vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
GENE, vol. 145, 1994, pages 69 - 73
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
"NCBI", Database accession no. WP _074495858.1
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N. ET AL.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI, vol. 15, no. 2, 2014, pages 2773 - 2793, XP055376889, DOI: 10.3390/ijms15022773
SAMBROOK ET AL., MOLECULAR CLONING, 2012
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, no. 1, 1986
SITNICKA ET AL.: "Functional Analysis of Genes", ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
"Manual of Methods for General Bacteriology", 1981, AMERICAN SOCIETY FOR BACTERIOLOGY
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
Download PDF: