Title:
NOVEL LACTOBACILLUS AND NOVEL LACTOBACILLUS-CONTAINING MEDICINE, FOOD, BEVERAGE AND FEED
Document Type and Number:
WIPO Patent Application WO/2015/004949
Kind Code:
A1
Abstract:
A Lactobacillus paracasei MCC 1849 (NITE BP-01633) strain having high IL-12-production-promoting effects is used as a component of a medicine, food, beverage, or feed to be used for promoting IL-12 production, immunostimulation, antiviral purposes, etc.
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Inventors:
TANAKA TOMOHIRO (JP)
IWABUCHI NORIYUKI (JP)
SATO YOHEI (JP)
SHIMIZU KANETADA (JP)
ODAMAKI TOSHITAKA (JP)
IWABUCHI NORIYUKI (JP)
SATO YOHEI (JP)
SHIMIZU KANETADA (JP)
ODAMAKI TOSHITAKA (JP)
Application Number:
PCT/JP2014/057319
Publication Date:
January 15, 2015
Filing Date:
March 18, 2014
Export Citation:
Assignee:
MORINAGA MILK INDUSTRY CO LTD (JP)
International Classes:
C12N1/20; A23K1/16; A23L1/30; A61K35/74; A61P31/12; A61P31/16; A61P37/04
Domestic Patent References:
| WO2012133827A1 | 2012-10-04 | |||
| WO2011027829A1 | 2011-03-10 | |||
| WO2012133827A1 | 2012-10-04 | |||
| WO2009005124A1 | 2009-01-08 | |||
| WO2011027829A1 | 2011-03-10 |
Foreign References:
| JP2009155221A | 2009-07-16 | |||
| JP2009155221A | 2009-07-16 |
Other References:
COEURET V ET AL.: "In vitro screening of potential probiotic activities of selected lactobacilli isolated from unpasteurized milk products for incorporationinto soft cheese", J. DAIRY RES., vol. 71, no. 4, November 2004 (2004-11-01), pages 451 - 460, XP008180088
TOMOHIRO TANAKA ET AL.: "Kanetsu Joken ga Lactobacillus paracasei MoLac-1 no IL -12 Yudo Kassei ni Oyobosu Eikyo", JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY TAIKAI KOEN YOSHISHU, vol. 2012, 5 March 2012 (2012-03-05), pages 392, XP008180106
NORIYUKI IWABUCHI ET AL.: "Takai IL -12 Yudo Kassei o Yusuru Nyusankin Lactobacillus paracasei MoLac-1 ni yoru Kansen Bogyo Sayo", JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY TAIKAI KOEN YOSHISHU, vol. 2012, 5 March 2012 (2012-03-05), pages 391, XP008180105
SHIDA K ET AL.: "Induction of interleukin-12 by Lactobacillus strains having a rigidcell wall resistant to intracellular digestion", J. DAIRY SCI., vol. 89, no. 9, 1 January 2006 (2006-01-01), pages 3306 - 3317, XP026957169
SHIDA K ET AL.: "Peptidoglycan from lactobacilli inhibits interleukin-12 production by macrophages induced by Lactobacillus casei through Toll-like receptor2-dependent and independent mechanisms", IMMUNOLOGY, vol. 128, no. 1-2, 1 September 2009 (2009-09-01), pages E858 - E869, XP055269298, DOI: 10.1111/J.1365-2567.2009.03095.X
INOUE R ET AL.: "Nucleic acids of Enterococcus faecalis strain EC -12 are potent Toll-like receptor 7 and 9 ligands inducing interleukin- 12 production from murine splenocytes and murine macrophage cell line J774.1", FEMS IMMUNOL. MED. MICROBIOL., vol. 61, no. 1, 1 January 2011 (2011-01-01), pages 94 - 102, XP055067355, DOI: 10.1111/J.1574-695X.2010.00752.X
ICHIKAWA S ET AL.: "ORALLY ADMINISTEREDI:10.1271/BBB.90058CASEI KW3110 INDUCES IN vivo IL -12 production", BIOSCI. BIOTECHNOL. BIOCHEM., vol. 73, no. 7, July 2009 (2009-07-01), pages 1561 - 1565, XP055269289, DOI: 10.1271/BBB.90058
TUO Y ET AL.: "In vitro assessment of immunomodulating activity of the two Lactobacillus strains isolated from traditional fermented milk", WORLD J. MICROBIOL. BIOTECHNOL., vol. 27, no. 3, 1 January 2011 (2011-01-01), pages 505 - 511, XP019882014, DOI: 10.1007/S11274-010-0482-8
DELCENSERIE V ET AL.: "Immunomodulatory effects of probiotics in the intestinal tract", CURR. ISSUES MOL. BIOL, vol. 10, no. 1-2, 1 January 2009 (2009-01-01), pages 37 - 54, XP055269295
DELCENSERIE, V. ET AL., CURR. ISSUES MOL. BIOL., vol. 10, 2008, pages 37 - 54
HORI T. ET AL., CLIN. DIAGN. LAB. IMMUNOL., vol. 9, 2002, pages 105 - 108
TAKEDA, K ET AL., CLIN. EXP. IMMUNOL, vol. 146, 2006, pages 109 - 115
OGAWA, T., CLIN. EXP. IMMUNOL., vol. 143, 2006, pages 103 - 109
SHIDA, K. ET AL., J. DAIRY SCI., vol. 89, 2006, pages 3306 - 3317
INOUE, R ET AL., FEMS IMMNOL. MED. MICROBIOL., vol. 61, 2011, pages 94 - 102
HUANG C.H.; LEE F.L., ANTONIE VAN LEEUWENHOEK, vol. 99, no. 2, 2011, pages 319 - 27
See also references of EP 2940124A4
TOMOHIRO TANAKA ET AL.: "Kanetsu Joken ga Lactobacillus paracasei MoLac-1 no IL -12 Yudo Kassei ni Oyobosu Eikyo", JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY TAIKAI KOEN YOSHISHU, vol. 2012, 5 March 2012 (2012-03-05), pages 392, XP008180106
NORIYUKI IWABUCHI ET AL.: "Takai IL -12 Yudo Kassei o Yusuru Nyusankin Lactobacillus paracasei MoLac-1 ni yoru Kansen Bogyo Sayo", JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY TAIKAI KOEN YOSHISHU, vol. 2012, 5 March 2012 (2012-03-05), pages 391, XP008180105
SHIDA K ET AL.: "Induction of interleukin-12 by Lactobacillus strains having a rigidcell wall resistant to intracellular digestion", J. DAIRY SCI., vol. 89, no. 9, 1 January 2006 (2006-01-01), pages 3306 - 3317, XP026957169
SHIDA K ET AL.: "Peptidoglycan from lactobacilli inhibits interleukin-12 production by macrophages induced by Lactobacillus casei through Toll-like receptor2-dependent and independent mechanisms", IMMUNOLOGY, vol. 128, no. 1-2, 1 September 2009 (2009-09-01), pages E858 - E869, XP055269298, DOI: 10.1111/J.1365-2567.2009.03095.X
INOUE R ET AL.: "Nucleic acids of Enterococcus faecalis strain EC -12 are potent Toll-like receptor 7 and 9 ligands inducing interleukin- 12 production from murine splenocytes and murine macrophage cell line J774.1", FEMS IMMUNOL. MED. MICROBIOL., vol. 61, no. 1, 1 January 2011 (2011-01-01), pages 94 - 102, XP055067355, DOI: 10.1111/J.1574-695X.2010.00752.X
ICHIKAWA S ET AL.: "ORALLY ADMINISTEREDI:10.1271/BBB.90058CASEI KW3110 INDUCES IN vivo IL -12 production", BIOSCI. BIOTECHNOL. BIOCHEM., vol. 73, no. 7, July 2009 (2009-07-01), pages 1561 - 1565, XP055269289, DOI: 10.1271/BBB.90058
TUO Y ET AL.: "In vitro assessment of immunomodulating activity of the two Lactobacillus strains isolated from traditional fermented milk", WORLD J. MICROBIOL. BIOTECHNOL., vol. 27, no. 3, 1 January 2011 (2011-01-01), pages 505 - 511, XP019882014, DOI: 10.1007/S11274-010-0482-8
DELCENSERIE V ET AL.: "Immunomodulatory effects of probiotics in the intestinal tract", CURR. ISSUES MOL. BIOL, vol. 10, no. 1-2, 1 January 2009 (2009-01-01), pages 37 - 54, XP055269295
DELCENSERIE, V. ET AL., CURR. ISSUES MOL. BIOL., vol. 10, 2008, pages 37 - 54
HORI T. ET AL., CLIN. DIAGN. LAB. IMMUNOL., vol. 9, 2002, pages 105 - 108
TAKEDA, K ET AL., CLIN. EXP. IMMUNOL, vol. 146, 2006, pages 109 - 115
OGAWA, T., CLIN. EXP. IMMUNOL., vol. 143, 2006, pages 103 - 109
SHIDA, K. ET AL., J. DAIRY SCI., vol. 89, 2006, pages 3306 - 3317
INOUE, R ET AL., FEMS IMMNOL. MED. MICROBIOL., vol. 61, 2011, pages 94 - 102
HUANG C.H.; LEE F.L., ANTONIE VAN LEEUWENHOEK, vol. 99, no. 2, 2011, pages 319 - 27
See also references of EP 2940124A4
Attorney, Agent or Firm:
KAWAGUCHI, Yoshiyuki et al. (JP)
Yoshiyuki Kawaguchi (JP)
Yoshiyuki Kawaguchi (JP)
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