NOVEL PROCESSES FOR PREPARING CAMPTOTHECIN DERIVATIVES

Title:

NOVEL PROCESSES FOR PREPARING CAMPTOTHECIN DERIVATIVES

Document Type and Number:

WIPO Patent Application WO/2024/020734

Kind Code:

A1

Abstract:

Provided are methods for preparing camptothecin derivatives and their synthetic precursors.

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Inventors:

XU FENG (CN)
KOZYTSKA MARIYA VOLODIMIRIVNA (US)
HAGUE ANDREW BRIAN (US)
CAMERON MARK (US)
CHETIA LAKSHINDRA (IN)
KATUPALAYAM RAVIKUMAR (IN)
ANNADASU RAMESH (IN)
PATIL SUDHIR TULSHIRAM (CN)
ZHANG JIANGKUN (CN)
SUDIPTO BHOWMICK (CN)

Application Number:

PCT/CN2022/107665

Publication Date:

February 01, 2024

Filing Date:

July 25, 2022

Export Citation:

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Assignee:

IMMUNOGEN INC (US)
XU FENG (CN)

International Classes:

C07D491/22; A61K31/4375; A61K47/50; A61P35/00

Domestic Patent References:

WO2020219287A1	2020-10-29
WO2021067861A1	2021-04-08

Foreign References:

CN1145365A

1997-03-19

Other References:

LI, WEI ET AL.: "Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates", ACS MED. CHEM. LETT., vol. 10, no. 10, 2019-09-06, XP055758576, ISSN: 1948-5875, DOI: 10.1021/acsmedchemlett.9b00301

Attorney, Agent or Firm:

KING & WOOD MALLESONS (CN)

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