Title:
OIL-BASED COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2019/098010
Kind Code:
A1
Abstract:
Provided is a method for blending a compound effective in preventing or improving aging of the skin into a chemically stable composition. Also provided is a method for increasing the uniform dispersibility of the compound in the composition. A compound represented by general formula (1), an isomer thereof, and/or a pharmacologically acceptable salt of these is dispersed in an oil agent having 0-2 hydroxyl groups to produce an oil-based composition, whereby decomposition of the compound is suppressed. A powder, solid fat, and/or semisolid fat is also included in the composition, whereby precipitation of the compound in the composition over time is suppressed. [In the formula, R1 represents a C1-4 linear or branched alkyl group substituted by a carboxyl group or a C1-4 linear or branched alkyl group substituted by a carboxylic acid ester group having a C1-4 alkyl chain, and R2 and R3 each independently represent a C1-4 linear or branched alkyl group.]
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Inventors:
DAIRAKU SACHIKO (JP)
TAKEUCHI SATOMI (JP)
TAKEUCHI SATOMI (JP)
Application Number:
PCT/JP2018/040287
Publication Date:
May 23, 2019
Filing Date:
October 30, 2018
Export Citation:
Assignee:
POLA CHEM IND INC (JP)
International Classes:
A61K8/70; A61K8/02; A61K8/31; A61K8/37; A61K8/64; A61K8/891; A61Q19/08
Domestic Patent References:
| WO1999043352A1 | 1999-09-02 | |||
| WO2001026685A1 | 2001-04-19 | |||
| WO2017221973A1 | 2017-12-28 | |||
| WO2001040263A1 | 2001-06-07 | |||
| WO1998027998A1 | 1998-07-02 | |||
| WO1999043352A1 | 1999-09-02 |
Foreign References:
| JP2005508873A | 2005-04-07 | |||
| JPH10245314A | 1998-09-14 | |||
| JP2002255847A | 2002-09-11 | |||
| JP2004123637A | 2004-04-22 | |||
| JPH04297446A | 1992-10-21 |
Other References:
ANONYMOUS: "Deliberation result report and examination report of POLA Wrinkle shot Medical Serum", PMDA.GO.JP, 27 July 2016 (2016-07-27), pages 1 - 4, XP055610347, Retrieved from the Internet [retrieved on 20190121]
ANONYMOUS: "Material of origin or discovery process and current status of usage in foreign countries...Documentation for POLA Wrinkle shot Medicla Serum, Summaries of Application Material for POLA Wrinkle shot Medical Serum", PMDA.GO.JP, 2016, XP055610350, Retrieved from the Internet
"Facial Serum, Pola, Japan , Pola Wrinkle Shot, ID# 4585815", MINTEL GNPD, January 2017 (2017-01-01), XP055706180, Retrieved from the Internet
See also references of EP 3711746A4
ANONYMOUS: "Material of origin or discovery process and current status of usage in foreign countries...Documentation for POLA Wrinkle shot Medicla Serum, Summaries of Application Material for POLA Wrinkle shot Medical Serum", PMDA.GO.JP, 2016, XP055610350, Retrieved from the Internet
"Facial Serum, Pola, Japan , Pola Wrinkle Shot, ID# 4585815", MINTEL GNPD, January 2017 (2017-01-01), XP055706180, Retrieved from the Internet
See also references of EP 3711746A4
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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