Title:
OLIGOPEPTIDE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/242339
Kind Code:
A1
Abstract:
The present invention provides an oligopeptide, a preparation method therefor, and an application thereof. The amino acid sequence of the oligopeptide is Phe-Pro-Gln-Tyr-Leu-Gln-Tyr-Pro-Tyr, and the IC50 of the oligopeptide to an angiotensin converting enzyme is 24.447 μg/mL. According to the present invention, the oligopeptide having an inhibiting effect on the angiotensin converting enzyme is obtained after performing enzymolysis, separation, and purification on a sheep milk casein protein, and the oligopeptide lays a foundation for application of a natural product antihypertensive peptide in the future.
More Like This:
Inventors:
QIAO ZIJIAO (CN)
HE YING (CN)
XIE KUI (CN)
NING YALI (CN)
YAN WEIBIN (CN)
CAO YONG (CN)
WANG JIAQI (CN)
PAN LINA (CN)
DAI ZHIYONG (CN)
LIU GUO (CN)
AN YANJUN (CN)
HOU YANMEI (CN)
LI HUIYU (CN)
TENG SHUANG (CN)
HE YING (CN)
XIE KUI (CN)
NING YALI (CN)
YAN WEIBIN (CN)
CAO YONG (CN)
WANG JIAQI (CN)
PAN LINA (CN)
DAI ZHIYONG (CN)
LIU GUO (CN)
AN YANJUN (CN)
HOU YANMEI (CN)
LI HUIYU (CN)
TENG SHUANG (CN)
Application Number:
PCT/CN2022/085017
Publication Date:
November 24, 2022
Filing Date:
April 02, 2022
Export Citation:
Assignee:
AUSNUTRIA DAIRY CHINA COMPANY LTD (CN)
HYPROCA NUTRITION CO LTD (CN)
HYPROCA NUTRITION CO LTD (CN)
International Classes:
C07K14/47; A23L33/18; A61K38/17; A61P9/12; C07K1/20; C12P21/06
Domestic Patent References:
| WO2005012542A1 | 2005-02-10 |
Foreign References:
| CN113321719A | 2021-08-31 | |||
| CN1894273A | 2007-01-10 | |||
| CN1680580A | 2005-10-12 | |||
| CN111548387A | 2020-08-18 | |||
| CN1784146A | 2006-06-07 |
Attorney, Agent or Firm:
CHANGSHA CHUWEI INTELLECTUAL PROPERTYAGENCY (GENERAL PARTNERSHIP) (CN)
Download PDF: